Molecular Research in Chronic Dermatoses, 2nd Edition
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 552
Special Issue Editors
Interests: melanoma; clinical dermatology; cancer biomarkers; basal cell carcinoma; psoriasis; dermatopathology; dermatosurgery; skin biology; cosmetology
Special Issues, Collections and Topics in MDPI journals
Interests: hidradenitis suppurativa; hair disorders; psoriasis; inflammatory skin disorders; dermatological surgery; comorbidities; itch; psychodermatology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic inflammatory dermatoses are a group of skin disorders characterized by recurrent and debilitating course and destructive influence on patients’ quality of life. The pathogenesis of most of them is not fully understood. Therefore, the treatment is challenging both for physicians and their patients, and the outcome is often unsatisfactory.
In recent years outstanding progress in understanding the molecular mechanisms behind the pathogenesis of inflammatory dermatoses has been made. The studies led to the development of new therapies, including biologics (chimeric, humanized, and human monoclonal antibodies) and their biosimilars, as well as systemic and topical small molecules (e.g. JAK inhibitors), which have revolutionized the management of patients suffering from chronic inflammatory dermatoses.
Nevertheless, there are still many unmet needs of currently available therapies. The insufficient availability and the high price of biologics impede their use in lower-income communities, while the adverse effects of JAK inhibitors may cause physicians hesitant about their prolonged use. Therefore, there is still a significant need for future, molecular research explaining the pathogenetic mechanisms leading to the development of skin lesions. In the future, these findings may build a foundation for new, targeted therapies, as well as for predicting disease course and its severity.
The special issue entitled “Molecular Research in Chronic Dermatoses, 2nd Edition” is now open for submission. Following with the first edition, our aim is to publish state of art articles about the molecular mechanisms in, among others, hidradenitis suppurativa, psoriasis, atopic dermatitis, alopecia areata, vitiligo, and chronic spontaneous urticaria. This Special Issue will accept review articles, original research, and updated information on the pathophysiology and molecular pathways.
Dr. Antonio Martorell-Calatayud
Dr. Piotr K. Krajewski
Guest Editors
Manuscript Submission Information
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Keywords
- dermatopathology
- dermatosurgery
- skin biology
- molecular biology
- genetics
- JAK inhibitors
- antibodies
