Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Bioorganic Chemistry and Medicinal Chemistry".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 950
Special Issue Editor
Interests: natural product; chemistry; medicinal chemistry; cancer biology; bioorganic chemistry; pharmacology; diabetes; synthetic chemistry; biology oriented synthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural products (NPs) have played a crucial role in the drug discovery process in order to treat numerous diseases. Plants, fungi, bacteria, and other natural sources produce NPs with intriguing chemical diversity illustrating interesting biological effects for numerous disease treatments. Notably, NP-based drugs are usually considered to be safer, cheaper, and easily available. Diabetes is one of the chronic disorders associated with high mortality risk. Unfortunately, the currently used drugs have been identified with one or more adverse effects. This indicates that there is still an urgent need for the development of novel antidiabetic drugs with a unique mechanism of action.
The focus of this Special Issue is on natural products (NPs)-based antidiabetic molecules and NPs-based synthetic antidiabetic compounds. Furthermore, this Issue will also place emphasis on the relationship between the chemical structure and the biological activity of the molecules at the molecular level together with applying bioinformatics in diabetes. Moreover, this Special Issue also welcomes articles on the antidiabetic effects of α-glucosidase, amylase, protein tyrosine phosphatase 1B (PTP1B), and dipeptidyl peptidase (DPP)-4 inhibition at the molecular level (kinetic studies). This Special Issue will also focus on the development of new therapeutic agents for diabetes treatment, employing the newest techniques of pharmacology, biotechnology, and genetic engineering. This Issue welcomes original articles, communications, and reviews dealing with diabetes treatment.
Dr. Hidayat HussainGuest Editor
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Keywords
- natural products
- natural product derivatives
- antidiabetic agents
- α-glucosidase inhibitors
- amylase inhibitors
- PTP1B inhibitors
- DPP-4 inhibitors
- molecular level
- kinetic studies
- in vitro studies
- in vivo studies
- computational methods
- mode of action
