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Women’s Special Issue Series: CIMB 2023

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1456

Special Issue Editors


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Guest Editor
Department of Computer, Control, and Management Engineering (DIAG), Sapienza University of Rome, 00179 Rome, Italy
Interests: biomedical engineering; computational biology; bioinformatics; systems biology; computational medicine; network medicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Département de Biologie, Université de Bretagne Occidentale, 29238 Brest, France
Interests: nutrition; homeostasis; immunology; cancer; thrombosis; neurobiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are excited to launch this Special Issue of CIMB, entitled “Women’s Special Issue Series: CIMB 2023”, in order to promote and support the contributions of women in molecular biology from all around the world.

We welcome submissions from all authors, irrespective of gender identity.

Topics relevant to this Special Issue include, but are not limited to:

  • Molecular biology;
  • Biochemistry;
  • Molecular plant sciences;
  • Molecular microbiology;
  • Molecular immunology;
  • Molecular genetics and genomics;
  • Molecular informatics;
  • Molecular oncology;
  • Molecular neurobiology;
  • Molecular pharmacology;
  • Molecular biophysics;
  • Molecular cell biology;
  • Molecular marine biology;
  • Molecular paleobiology;
  • Molecular physiology;
  • Molecular radiation biology;
  • Molecular reproductive biology;
  • Molecular zoology;
  • Structural biology;
  • Systems biology.

We welcome submissions from all authors, irrespective of gender.

Dr. Giulia Fiscon
Dr. Nathalie Guriec
Guest Editors

Women’s Special Issue Series

This Special Issue is part of CIMB’s Women’s Special Issue Series, hosted by women editors for women researchers. The Series advocates the advancement of women in science. We invite contributions to the Special Issue whose lead authors identify as women. The submission of articles with all-women authorship is especially encouraged. However, we do welcome articles from all authors, irrespective of gender.

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical engineering
  • computational biology
  • bioinformatics
  • systems biology
  • computational medicine

Published Papers (1 paper)

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Research

15 pages, 4377 KiB  
Article
PCID2 Subunit of the Drosophila TREX-2 Complex Has Two RNA-Binding Regions
by Yulia A. Vdovina, Maria M. Kurshakova, Sofia G. Georgieva and Daria V. Kopytova
Curr. Issues Mol. Biol. 2023, 45(7), 5662-5676; https://doi.org/10.3390/cimb45070357 - 4 Jul 2023
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Abstract
Drosophila PCID2 is a subunit of the TREX-2 mRNA nuclear export complex. Although the complex has long been studied in eukaryotes, it is still unclear how TREX-2 interacts with mRNA in multicellular organisms. Here, the interaction between Drosophila PCID2 and the ras2 RNA [...] Read more.
Drosophila PCID2 is a subunit of the TREX-2 mRNA nuclear export complex. Although the complex has long been studied in eukaryotes, it is still unclear how TREX-2 interacts with mRNA in multicellular organisms. Here, the interaction between Drosophila PCID2 and the ras2 RNA was studied by EMSA. We show that the C-terminal region of the WH domain of PCID2 specifically binds the 3′-noncoding region of the ras2 RNA. While the same region of PCID2 interacts with the Xmas-2 subunit of the TREX-2 complex, PCID2 interacts with RNA independently of Xmas-2. An additional RNA-binding region (M region) was identified in the N-terminal part of the PCI domain and found to bind RNA nonspecifically. Point mutations of evolutionarily conserved amino acid residues in this region completely abolish the PCID2–RNA interaction, while a deletion of the C-terminal domain only partly decreases it. Thus, the specific interaction of PCID2 with RNA requires nonspecific PCID2–RNA binding. Full article
(This article belongs to the Special Issue Women’s Special Issue Series: CIMB 2023)
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