Molecular Research in Osteoarthritis and Osteoarticular Diseases
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 1790
Special Issue Editor
Interests: osteoarthritis; osteoclasts; bone homeostasis; skeletal stem cells; energy metabolism; bioinformatics; epigenetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
For many years, osteoarthritis and osteoarticular diseases have been the most common diseases affecting the aging population, characterized by dysregulation of bone homeostasis and deformations of bone and cartilage structures. A good balance between anabolism and catabolism maintains the homeostasis of bone and cartilage metabolism. However, under pathological conditions, this balance is disrupted and transformed into a state of metabolic imbalance, leading to diseases such as osteoporosis and osteoarthritis.
Currently, of all the tissues that make up synovial joints, articular cartilage remains the focus of research. But cartilage, synovium, subchondral bone, and the interactions between these tissues are core components in the development of osteoarthritis. Low-grade inflammation and metabolic changes occur as individuals age, and it is the interplay between different cells, their environment, and mechanical and molecular factors that make this disease process so complex.
This special issue explores recent advances at the molecular level in osteoarthritis and bone and joint diseases. It focuses on understanding the pathophysiology and molecular mechanisms of the disease, molecular mechanisms underlying bone metabolism and cartilage metabolism, new therapeutic strategies, cutting-edge technologies, and emerging trends in treatment. By fostering collaboration among experts, we will further study the underlying mechanisms of osteoarthritis, bone and joint diseases and discover new drugs or target proteins for the treatment of these diseases and their eventual regeneration.
Dr. Ye Liu
Guest Editor
Manuscript Submission Information
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Keywords
- osteoarthritis
- cartilage regeneration
- bioinformatics
- biomarkers
- inflammation
- cartilage
- metabolic imbalance
