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Chemosensors
Special Issues
Chemosensors in Biological Challenges, Volume II
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Chemosensors in Biological Challenges, Volume II

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Applied Chemical Sensors".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 3520

Special Issue Editors

Dr. Petri A. Turhanen

E-Mail Website
Guest Editor
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
Interests: organic chemistry; medicinal chemistry; bisphosphonates; atp analogues; high performance counter current chromatography (HPCCC); green chemistry; synthesis methods
Special Issues, Collections and Topics in MDPI journals
Dr. Juri M. Timonen

E-Mail Website
Guest Editor
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland
Interests: synthetic chemistry; organic chemistry; coumarins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue comprises selected papers related to chemosensors in biological challenges . Biological challenges combine life and health sciences with bio- and natural sciences. In this Special Issue, chemosensors are used to address the challenges of biological environments from the perspective of drug development, environmental sciences, and the circular economy. Questions are answered using the following chemical and biological methods and technologies:

  • Bioanalytical chemistry;
  • Electrochemical devices and sensors;
  • Optical chemical sensors;
  • Imaging;
  • Spectroscopy;
  • Analytical apparatus;
  • Quantitative analysis;
  • Microfluidic devices—lab-on-a-chip, single-molecule sensing;
  • Nanosensors;
  • Medical analyzers;
  • Gas sensors—electronic nose and electronic tongue ones;
  • pH sensors—humidity sensors.

Dr. Petri A. Turhanen
Dr. Juri M. Timonen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

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13 pages, 580 KiB  
Article
Diabetes Monitoring through Urine Analysis Using ATR-FTIR Spectroscopy and Machine Learning
by Sajid Farooq and Denise Maria Zezell
Chemosensors 2023, 11(11), 565; https://doi.org/10.3390/chemosensors11110565 - 15 Nov 2023
Viewed by 1532
Abstract
Diabetes mellitus (DM) is a widespread and rapidly growing disease, and it is estimated that it will impact up to 693 million adults by 2045. To cope this challenge, the innovative advances in non-destructive progressive urine glucose-monitoring platforms are important for improving diabetes [...] Read more.
Diabetes mellitus (DM) is a widespread and rapidly growing disease, and it is estimated that it will impact up to 693 million adults by 2045. To cope this challenge, the innovative advances in non-destructive progressive urine glucose-monitoring platforms are important for improving diabetes surveillance technologies. In this study, we aim to better evaluate DM by analyzing 149 urine spectral samples (86 diabetes and 63 healthy control male Wistar rats) utilizing attenuated total reflection–Fourier transform infrared (ATR-FTIR) spectroscopy combined with machine learning (ML) methods, including a 3D discriminant analysis approach—3D–Principal Component Analysis–Linear Discriminant Analysis (3D-PCA-LDA)—in the ‘bio-fingerprint’ region of 1800–900 cm−1. The 3D discriminant analysis technique demonstrated superior performance compared to the conventional PCA-LDA approach with the 3D-PCA-LDA method achieving 100% accuracy, sensitivity, and specificity. Our results show that this study contributes to the existing methodologies on non-destructive diagnostic methods for DM and also highlights the promising potential of ATR-FTIR spectroscopy with an ML-driven 3D-discriminant analysis approach in disease classification and monitoring. Full article
(This article belongs to the Special Issue Chemosensors in Biological Challenges, Volume II)
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Review

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34 pages, 7042 KiB  
Review
Wearable Chemosensors in Physiological Monitoring
by Zeyi Tang, Tianrui Cui, Houfang Liu, Jinming Jian, Ding Li, Yi Yang and Tianling Ren
Chemosensors 2023, 11(8), 459; https://doi.org/10.3390/chemosensors11080459 - 15 Aug 2023
Viewed by 1493
Abstract
The development of flexible electronic technology has led to significant advancements in wearable sensors. In the past decades, wearable chemosensors have received much attention from researchers worldwide due to their high portability, flexibility, lightweight, and adaptability. It allows real-time access to the user’s [...] Read more.
The development of flexible electronic technology has led to significant advancements in wearable sensors. In the past decades, wearable chemosensors have received much attention from researchers worldwide due to their high portability, flexibility, lightweight, and adaptability. It allows real-time access to the user’s physiological status at the molecular level to analyze their health status. Therefore, it can be widely used in the field of precision medicine. This review introduces the sensing mechanisms of wearable chemosensors and recent progress in wearable sweat and interstitial fluid-based chemosensors. The complexities of wearable chemosensors are not to be underestimated, as there are considerable challenges in this field. This review aims to shed light on the difficulties associated with designing wearable sweat and interstitial fluid-based chemosensors and their potential development directions. Full article
(This article belongs to the Special Issue Chemosensors in Biological Challenges, Volume II)
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