Special Issue "Targeting the Vulnerabilities of Oncogene Activation"
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 8719
Interests: biochemistry; genetics and molecular biology medicine pharmacology; toxicology and pharmaceutics immunology and microbiology chemistry neuroscience multidisciplinary agricultural and biological sciences
Special Issues, Collections and Topics in MDPI journals
This issue presents novel findings on signaling changes induced as part of the tumorigenesis process. While the mutation of oncogenes and loss of tumor suppressor genes enable tumor cells to survive and thrive in hostile environments, they also bring metabolic vulnerabilities that can be exploited. These vulnerabilities include induction of tyrosine kinases, dependence on novel substrates, and adaptations to respiration. Targeting these vulnerabilities will lead to novel therapies for both benign and malignant disorders
Prof. Dr. Jack L. Arbiser
Manuscript Submission Information
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