A Special Issue on Tumor Stroma
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (31 March 2020) | Viewed by 94394
Interests: Tumor modeling; Tumor microenvironment; Drug resistance
Interests: tumor microenvironment; cancer models; 3D cultures; drug resistance; fibrin; fibronectin
Special Issues, Collections and Topics in MDPI journals
Our evolving understanding of cancer indicates that the tumor stroma is a dynamic environment that plays significant roles in tumor growth, drug resistance, and cancer cell invasion and metastasis. Tumor stroma undergoes biochemical and physical alterations in the protein composition, matrix protein architecture, and tissue mechanical properties that collectively accommodate the emerging needs of cancer cells during different stages of the disease. The stromal cells including fibroblast cells, vascular cells, and immune cells also act in concert to regulate a broad range of functions of cancer cells and their resistance to therapeutics. This special issue will report both recent developments and expert opinion on our understanding of tumor stroma as a driver of the disease as well as its potential as a therapeutic target. We welcome submissions that use different approaches such as three-dimensional cell cultures, organoids, and/or animal models to study the role of specific stromal cells and the extracellular matrix on phenotypic and functional regulation of solid cancers and elucidate underlying molecular mechanisms.
Dr. Hossein Tavana
Dr. Luis Solorio
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.