A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 April 2016) | Viewed by 124642
2. Department of Medicine, University of Oklahoma, Oklahoma City, OK 73126, USA
Interests: Immunotherapy; CAR-T cells; tumor microenvironment; checkpoint protein; hypoxia; tumor survival signaling
Special Issues, Collections and Topics in MDPI journals
Cancer immunotherapy (therapy that uses a person's immune system to fight cancer) has become an important field of oncology. There are four main types of immunotherapies: monoclonal antibodies; cancer vaccines; checkpoint inhibitors; and non-specific cancer immunotherapies (therapies that do not target cancer specifically, but stimulate immune cells that can lead to anti-cancer immune response, such as interleukins, cytokines, interferons, and others). Tumors express ligands to immune checkpoint proteins, such as PD-1 (programmed cell death 1) and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), mediating block of immune response. Thus, the development of inhibitors of these immune checkpoint pathways is a promising area of immune therapeutics. In addition, tumors express tumor antigens that can be targeted with antibodies; antibody-drug conjugates; chimeric antigen receptor (CAR) T cells; or by other approaches. Dendritic cell vaccine is another important immunotherapy approach against cancer. This Special Issue is focused on recent immunotherapy approaches, novel immune therapeutics, and immunology signaling pathways in cancer.
Dr. Vita Golubovskaya
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- CAR-T cell
- dendritic cell
- tumor antigen
- monoclonal antibody