Advances in Surgery of Head and Neck Squamous Cell Carcinoma

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 20 September 2024 | Viewed by 1466

Special Issue Editor


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Guest Editor
Department of Otorhinolaryngology Head and Neck Surgery, Erasmus MC, 3015 GD Rotterdam, The Netherlands
Interests: head and neck cancer; sinonasal/skullbase tumors; translational research; tumor recurrence and distant metastasis; tumor microenvironment; tumor heterogeneity
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Special Issue Information

Dear Colleagues,

Head and neck squamous cell carcinoma is a type of cancer that affects the tissues in the head and neck region. It can be a challenging disease to treat, but advances in surgery have made the process much more successful. Over the years, surgeons have developed new techniques and technologies that allow for more precise and effective removal of cancerous cells. This has led to better outcomes for patients and a higher likelihood of long-term survival.

Some of the key advances in surgery for head and neck squamous cell carcinoma include minimally invasive techniques, precision-image-guided surgery, and the use of robots to assist with surgery. These innovations have helped reduce complications, speed up recovery times for patients, and improve adequate resections.

Overall, the field of surgery for head and neck squamous cell carcinoma is rapidly advancing, and patients can expect to benefit from these improvements in the years to come.

In this Special Issue, we aim to collect original research articles and review articles to present and discuss data on surgical advances in head and neck squamous cell carcinoma.

Dr. José Angelito U. Hardillo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck squamous cell carcinoma
  • surgery
  • outcomes
  • minimally invasive techniques
  • precision-image-guided surgery

Published Papers (2 papers)

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Research

16 pages, 237 KiB  
Article
Predictors for Success and Failure in Transoral Robotic Surgery—A Retrospective Study in the North of the Netherlands
by Alexandra G. L. Toppenberg, Thomas S. Nijboer, Wisse G. W. J. van der Laan, Jan Wedman, Leonora Q. Schwandt, Robert E. Plaat, Max J. H. Witjes, Inge Wegner and Gyorgy B. Halmos
Cancers 2024, 16(8), 1458; https://doi.org/10.3390/cancers16081458 - 11 Apr 2024
Viewed by 512
Abstract
Transoral Robotic Surgery (TORS) is utilized for treating various malignancies, such as early-stage oropharyngeal cancer and lymph node metastasis of an unknown primary tumor (CUP), and also benign conditions, like obstructive sleep apnea (OSA) and chronic lingual tonsillitis. However, the success and failure [...] Read more.
Transoral Robotic Surgery (TORS) is utilized for treating various malignancies, such as early-stage oropharyngeal cancer and lymph node metastasis of an unknown primary tumor (CUP), and also benign conditions, like obstructive sleep apnea (OSA) and chronic lingual tonsillitis. However, the success and failure of TORS have not been analyzed to date. In this retrospective observational multicenter cohort study, we evaluated patients treated with TORS using the da Vinci surgical system. Success criteria were defined as identification of the primary tumor for CUP, >2 mm resection margin for malignant conditions, and improvement on respiratory polygraphy and tonsillitis complaints for benign conditions. A total of 220 interventions in 211 patients were included. We identified predictors of success, such as low comorbidity status ACE-27, positive P16 status, and lower age for CUP, and female gender and OSA severity for benign conditions. For other malignancies, no predictors for success were found. Predictors of failure based on postoperative complications included high comorbidity scores (ASA) and anticoagulant use, and for postoperative pain, younger age and female gender were identified. This study provides valuable insights into the outcomes and predictors of success and failure in TORS procedures across various conditions and may also help in patient selection and counseling. Full article
(This article belongs to the Special Issue Advances in Surgery of Head and Neck Squamous Cell Carcinoma)
17 pages, 7495 KiB  
Article
Mixed Reality as a Digital Visualisation Solution for the Head and Neck Tumour Board: Application Creation and Implementation Study
by Nadia Karnatz, Michael Schwerter, Shufang Liu, Aida Parviz, Max Wilkat and Majeed Rana
Cancers 2024, 16(7), 1392; https://doi.org/10.3390/cancers16071392 - 31 Mar 2024
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Abstract
The preparation and implementation of interdisciplinary oncological case reviews are time-consuming and complex. The variety of clinical and radiological information must be presented in a clear and comprehensible manner. Only if all relevant patient-specific information is demonstrated in a short time frame can [...] Read more.
The preparation and implementation of interdisciplinary oncological case reviews are time-consuming and complex. The variety of clinical and radiological information must be presented in a clear and comprehensible manner. Only if all relevant patient-specific information is demonstrated in a short time frame can well-founded treatment decisions be made on this basis. Mixed reality (MR) technology as a multimodal interactive user interface could enhance understanding in multidisciplinary collaboration by visualising radiological or clinical data. The aim of the work was to develop an MR-based software prototype for a head and neck tumour board (HNTB) to support clinical decision-making. The article describes the development phases and workflows in the planning and creation of a MR-based software prototype that were required to meet the multidisciplinary characteristics of a HNTB. Full article
(This article belongs to the Special Issue Advances in Surgery of Head and Neck Squamous Cell Carcinoma)
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