Dear Colleagues,

Obesity is a significant public health concern due to its close link with metabolic comorbidities, such as type 2 diabetes, dyslipidemia, liver diseases, and cardiovascular diseases. Evidence suggests that excessive or inappropriate nutrient intake triggers chronic inflammatory responses in tissues that regulate metabolic homeostasis, leading to altered metabolic pathways, insulin resistance, and systemic metabolic dysfunction. Nutritional interventions have emerged as effective strategies for managing obesity and associated metabolic disorders.

In this Special Issue, we aim to cover the molecular significance of both macro- and micro-nutrients, as well as the current dietary recommendations. We will explore the primary metabolic pathways and molecular mechanisms in which each nutrient plays a role, and their contribution to the development of obesity and/or metabolic diseases. Importantly, gut microbiota are crucial in regulating the metabolic response to nutrient intake. As such, we aim to gain a mechanistic understanding of how nutrients and the intestinal microbiota may contribute to the metabolic health of the human host. By doing so, we hope to shed light on the pathogenesis of various common metabolic disorders including, but not limited to, obesity, type 2 diabetes, non-alcoholic liver disease, cardiometabolic diseases and malnutrition.

This Special Issue will focus on novel strategies and molecular mechanisms, as well as nutritional approaches to tackle obesity and its associated metabolic disturbances.

This Special Issue of the Biomolecules Journal, entitled “Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives”, aims to solicit original research papers or review articles on the current state of research in this field, including both discovery and preclinical studies.

We look forward to your contributions to this research field.

Dr. Marion Korach-André
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• diet
• nutrients
• obesity
• inflammation
• fat
• glucose intolerance
• insulin resistance
• fatty liver disease
• metabolic syndrome