Biology and Function of Inflammasomes
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 379
Special Issue Editor
Interests: inflammasome, innate immunity, inflammation, GPCR19, cancer immunotherapy; single domain antibody therapeutics
Special Issue Information
Dear Colleagues,
Inflammasomes are intracellular multiprotein complexes that play a fundamental role in the immune system. Inflammasomes, comprised of sensors, adaptors, and caspase-1, control the maturation of cytokines (IL-1 and IL-18) and induce pyroptosis. The dysregulation of inflammasomes is associated with a number of inflammatory conditions, such as metabolic disorders, diabetes, cardiovascular diseases, neurodegenerative diseases, inflammatory bowel disease, kidney injury, skin inflammation, and infectious diseases. As inflammasomes respond to a broad range of medically relevant stimuli, inflammasomes have become a highly desirable drug target with which to treat a wide range of human diseases.
This Special Issue, “Biology and Function of Inflammasomes”, welcomes original research and review articles in the field, with a focus on, but not limited to, the molecular basis, pathogenesis, inhibitor development, and therapeutics related to inflammasomes.
Prof. Dr. Seung-Yong Seong
Guest Editor
Manuscript Submission Information
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Keywords
- damage-associated molecular patterns
- DAMPs
- pattern recognition receptor
- immune inflammatory response
- inflammasome
