Inflammatory Cells and Repair
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 82
Special Issue Editors
Interests: stem cells; chemokines; macrophagse; CXCR4; SDF-1; iPS cells
Special Issues, Collections and Topics in MDPI journals
Interests: stem cell; regeneration
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Reports revealing the relationship between inflammation and tissue repair have increased in number, especially in the field of neurological and cardiovascular research. In regenerative research, the inhibition of inflammation is a key issues after transplanting grafts consisting of various materials. However, at the same time, inflammation can trigger a subsequent repair process. The phagocytosis of dead cells or microorganisms by innate immune cells begins, and simultaneously, these innate immune cells may contact the repair cells. Without this innate process, repair cannot be fully completed. Thus, achieving a balance between the repair and damage of inflammatory cells is essential. If this balance fails, inflammation becomes chronic and difficult to repair. Upon the development of inflammation, inflammatory cells and tissue cells secrete paracrine factors such as cytokines, chemokines, and alarmins, which may stimulate various cells. Moreover, extracellular vesicles (EVs) are released, which contain cytokines and non-coding RNAs, such as microRNAs, that, consequently, influence the biology of their target cells. These factors may be used for communication among various cells. However, these factors may contribute to both chronic inflammation and repair. Although the balance is important for the repair and regeneration of tissues, the best way to achieve it has not yet been clarified.
For this Special Issue, we invite authors to submit original research and review articles, mainly, though not necessarily solely, in the field of cardiovascular health. Any papers related to communication, inflammation, and the repair processes are welcome.
Dr. Nanako Kawaguchi
Dr. Toshio Nakanishi
Guest Editors
Manuscript Submission Information
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Keywords
- inflammation
- repair
- damage
