New Sights of 3D Printing in Bioengineering: Updates and Directions

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biofabrication and Biomanufacturing".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 3082

Special Issue Editors


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Guest Editor
Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA
Interests: 3D bioprinting; 3D printing; continuous manufacturing; drug formulation and delivery; implantable medical devices; smart biomaterials
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Guest Editor
Department of Pharmaceutical Sciences and Experimental Therapeutics, The University of Iowa, Iowa City, IA, USA
Interests: 3D printing; devices; gas sensing; nanoparticles

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Guest Editor
Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA
Interests: 3D printing; devices; nanoparticles

Special Issue Information

Dear Colleagues,

A few years ago, researchers have been inspired by the promise of 3D Printing to produce complex biomedical devices, design better instruments, create patient specific devices, deliver drugs, replace lost tissues, guide wound healing, and regenerate tissues. From pre-surgical models to tooling molds and instrument prototypes, 3D Printing has evolved to create one-of-a-kind devices, implants, scaffolds for tissue engineering, diagnostic platforms, and drug delivery systemsThis highlights the fact that, numerous technical, regulatory, and commercial limitations must be overcome before 3D Printing can reach its full potential in biomedical applications.

The aim of this Special Issue, entitled “New sight of 3D printing in bioengineering: Updates and Directions, is to make relevant work known to our colleagues in the field. To achieve this, the Special Issue, edited by Professor Mo Maniruzzaman and Dr. L. R. Jaidev,  Dr. Niloofar Heshmati Aghda, invites scientists to submit research articles, review articles, and short communications focused on this topic.

We look forward to your valuable contributions to make this Special Issue a reference resource for future researchers in the field of 3D printing in bioengineering.

Dr. Mo Maniruzzaman
Dr. L. R. Jaidev
Dr. Niloofar Heshmati Aghda
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

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12 pages, 4511 KiB  
Article
Personalized 3D Printed Eye Gear for Microscopic Surgeons Amidst and beyond COVID-19
by Ramandeep Singh, Rajdeep Singh and Ashish Suri
Bioengineering 2023, 10(10), 1129; https://doi.org/10.3390/bioengineering10101129 - 26 Sep 2023
Viewed by 990
Abstract
The COVID-19 pandemic underscored the need for enhanced protective measures for healthcare workers, particularly surgeons, who face a heightened risk of exposure to infectious aerosols. However, conventional eye protection equipment such as face shields, goggles, or glasses often leads to ergonomic discomfort and [...] Read more.
The COVID-19 pandemic underscored the need for enhanced protective measures for healthcare workers, particularly surgeons, who face a heightened risk of exposure to infectious aerosols. However, conventional eye protection equipment such as face shields, goggles, or glasses often leads to ergonomic discomfort and a reduced field of view (FOV), impeding surgeons’ ability to perform microsurgical procedures with precision and ease. To address these limitations, this study aimed to develop personalized 3D-printed eye gear for microscopic surgeons based on facial anthropometry data. 3D scanning was employed to obtain facial data from ten neurosurgery residents. Utilizing computer-aided designing, eye gears tailored to the unique facial features of each participant were developed. Finite element analysis-based contact simulation was used to assess the pressure exerted by the eye gear. Multi-material 3D printing was employed to fabricate the personalized eye gear. Participants, while donning the eye gear, engaged in simulation-based micro suturing tasks at various magnifications of the operating microscope, and marked the FOV range. They provided feedback scores (1–10) on the effectiveness of the eye gear through a Likert scale questionnaire (Q1-Q8). Finite element analysis demonstrated uniform strain distribution on the face, indicating that the edges of the customized eye gear fit exactly to the user’s face. The average scores for the questionnaire Q1 to Q8 ranged from 6.8 to 8.5, with an overall mean score of 7.6. This indicates that the developed eye gear was simple to use and did not cause any discomfort. Additionally, the average reduction in the FOV was only 10.93% across the different operating microscope magnifications. These findings highlight eye gear’s potential to alleviate discomfort and enhance precision in microscopic surgeries. Consequently, personalized 3D-printed eye gear offers a promising solution for providing surgeons with a safe environment while preserving the benefits of the operating microscope. Full article
(This article belongs to the Special Issue New Sights of 3D Printing in Bioengineering: Updates and Directions)
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Review

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21 pages, 4771 KiB  
Review
Characterization of Biocompatibility of Functional Bioinks for 3D Bioprinting
by Jinku Kim
Bioengineering 2023, 10(4), 457; https://doi.org/10.3390/bioengineering10040457 - 09 Apr 2023
Cited by 4 | Viewed by 1764
Abstract
Three-dimensional (3D) bioprinting with suitable bioinks has become a critical tool for fabricating 3D biomimetic complex structures mimicking physiological functions. While enormous efforts have been devoted to developing functional bioinks for 3D bioprinting, widely accepted bioinks have not yet been developed because they [...] Read more.
Three-dimensional (3D) bioprinting with suitable bioinks has become a critical tool for fabricating 3D biomimetic complex structures mimicking physiological functions. While enormous efforts have been devoted to developing functional bioinks for 3D bioprinting, widely accepted bioinks have not yet been developed because they have to fulfill stringent requirements such as biocompatibility and printability simultaneously. To further advance our knowledge of the biocompatibility of bioinks, this review presents the evolving concept of the biocompatibility of bioinks and standardization efforts for biocompatibility characterization. This work also briefly reviews recent methodological advances in image analyses to characterize the biocompatibility of bioinks with regard to cell viability and cell-material interactions within 3D constructs. Finally, this review highlights a number of updated contemporary characterization technologies and future perspectives to further advance our understanding of the biocompatibility of functional bioinks for successful 3D bioprinting. Full article
(This article belongs to the Special Issue New Sights of 3D Printing in Bioengineering: Updates and Directions)
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