Recent Advances in Probiotics Application on Animal Health

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1933

Special Issue Editor


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Guest Editor
Laboratory of Nutritional Physiology and Feeding, Department of Animal Science, Agricultural University of Athens, Athens, Greece
Interests: gut ecosystem; probiotics; phytogenics; microbiota; broiler nutrition

Special Issue Information

Dear Colleagues,

Probiotics are defined as “mono or mixed strains of living microorganisms which confer a desirable health benefit on the host when used adequately”. Although a cumulative body of evidence shows that probiotics and their metabolites could directly or indirectly impact gut microbiota and host immune functions, there is a lack of understanding of how probiotics influence the gut ecosystem. The proposed modes of action include enhancing epithelial barrier integrity, competitive exclusion, the secretion of bacteriocins, interference with quorum-sensing signaling agents, and immunomodulation. However, the overall efficiency of probiotics is dictated by factors such as the optimal selection of microbial strains; the use of a proper dose; and the species, age, and dynamics of the gastrointestinal (GI) microbial communities of the animal.

This Special Issue welcomes and encourages original research papers (in vivo or in vitro studies) and reviews on the recent advances in probiotics application on animal health—for example, how probiotics affect productivity; health biomarkers; GI health; the beneficial effects of probiotics on GI microbiota; and the effect of probiotics in the quorum-sensing signaling of microbial populations, in host signaling and the immune system, and in pathogen exclusion. The exploration of the role of probiotics could also be captured by modern approaches of metagenomics, meta-transcriptomics, and integrated omics, which enable an understanding of the probiotic mode of action on GI health and host immune function.

Dr. Irida Palamidi
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • probiotics
  • animal health
  • microbiota
  • immune system
  • quorum sensing
  • gut
  • host signaling
  • productivity
  • health biomarkers

Published Papers (2 papers)

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Research

17 pages, 2323 KiB  
Article
Evidence for Beneficial Physiological Responses of the Land Snail Cornu aspersum to Probiotics’ (Lactobacillus plantarum) Dietary Intervention
by Efstratios Efstratiou, Konstantinos Feidantsis, Vasiliki Makri, Alexandra Staikou and Ioannis A. Giantsis
Animals 2024, 14(6), 857; https://doi.org/10.3390/ani14060857 - 11 Mar 2024
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Abstract
A large variety of microorganisms ingested with food constitute animals’ intestinal microflora, enhancing and maintaining the homeostasis of the host. Rations enriched with probiotics are a method recommended to prevent undesirable conditions. To date, research has been limited to farmed animals and reared [...] Read more.
A large variety of microorganisms ingested with food constitute animals’ intestinal microflora, enhancing and maintaining the homeostasis of the host. Rations enriched with probiotics are a method recommended to prevent undesirable conditions. To date, research has been limited to farmed animals and reared fish, creating a knowledge gap concerning the effect of probiotics on the growth rate, physiological responses, and energy metabolism of invertebrates such as the land snail Cornu aspersum. Herein, juvenile snails (26.23 ± 0.5 mm shell diameter and 8.23 ± 1.02 g body weight) were fed L. plantarum probiotic-enriched rations in two different proportions (1.25 mg and 2.5 mg), and their growth rate was monitored for three months. Additionally, the RNA/DNA and Bax/Bcl-2 ratios, HSP gene expression and protein levels, and ND2 expression, were measured in the hepatopancreas, digestive tract, and mantle. Although the snails’ growth rate was not affected, the RNA/DNA ratio presented an increase in various tissues, indicating an intense physiological response. Also, probiotic administration demonstrated low levels of the Bax/Bcl-2 ratio. HSP levels were higher in the presence of probiotics, probably signaling an attempt by the animal to face potentially stressful situations. Finally, ND2 expression levels in the hepatopancreas indicate intense metabolic and antioxidant activity. Full article
(This article belongs to the Special Issue Recent Advances in Probiotics Application on Animal Health)
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19 pages, 4346 KiB  
Article
Effects of Dietary Limosilactobacillus fermentum and Lacticaseibacillus paracasei Supplementation on the Intestinal Stem Cell Proliferation, Immunity, and Ileal Microbiota of Broiler Chickens Challenged by Coccidia and Clostridium perfringens
by Shuangshuang Guo, Wenfei Tong, Ya Qi, Meihan Jiang, Peng Li, Zhengfan Zhang, Qunbing Hu, Zhuan Song and Binying Ding
Animals 2023, 13(24), 3864; https://doi.org/10.3390/ani13243864 - 15 Dec 2023
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Abstract
This study was conducted to investigate effects of dietary Limosilactobacillus fermentum and Lacticaseibacillus paracasei supplementation on the intestinal stem cell proliferation, immunity, and ileal microbiota of broiler chickens challenged by coccidia and Clostridium perfringens. A total of 336 one-day-old Ross 308 chickens [...] Read more.
This study was conducted to investigate effects of dietary Limosilactobacillus fermentum and Lacticaseibacillus paracasei supplementation on the intestinal stem cell proliferation, immunity, and ileal microbiota of broiler chickens challenged by coccidia and Clostridium perfringens. A total of 336 one-day-old Ross 308 chickens were randomly assigned into four groups. Chickens in the control (CTR) group were fed basal diet, and chickens in the three challenged groups were fed basal diets supplemented with nothing (CCP group), 1.0 × 109 CFU/kg L. fermentum (LF_CCP group), and 1.0 × 109 CFU/kg L. paracasei (LP_CCP group), respectively. All challenged birds were infected with coccildia on day 9 and Clostridium perfringens during days 13–18. The serum and intestinal samples were collected on days 13 and 19. The results showed that L. fermentum significantly increased jejunal gene expression of cdxB (one of the intestinal stem cell marker genes) on day 13. Additionally, L. fermentum significantly up-regulated mRNA levels of JAK3 and TYK2 and tended to increase STAT6 mRNA expression in jejunum on day 19. In the cecal tonsil, both L. fermentum and L. paracasei decreased mRNA expression of JAK2 on day 13, and L. fermentum down-regulated JAK1-2, STAT1, and STAT5-6 gene expressions on day 19. Ileal microbiological analysis showed that coccidial infection increased the EscherichiaShigella, Lactobacillus, and Romboutsia abundance and decreased Candidatus_Arthromitus richness on day 13, which were reversed by Lactobacillus intervention. Moreover, Lactobacilli increased ileal Lactobacillus richness on day 19. In conclusion, Lactobacilli alleviated the impairment of intestinal stem cell proliferation and immunity in coccidia- and C. perfringens-challenged birds via modulating JAK/STAT signaling and reshaping intestinal microflora. Full article
(This article belongs to the Special Issue Recent Advances in Probiotics Application on Animal Health)
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