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The Pathway to Solutions: Diagnosing and Treating Viral Diseases of...
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The Pathway to Solutions: Diagnosing and Treating Viral Diseases of Small Ruminants

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Small Ruminants".

Deadline for manuscript submissions: closed (15 March 2024) | Viewed by 2983

Special Issue Editors

Dr. Delia Lacasta

E-Mail Website
Guest Editor
Faculty of Veterinary Medicine, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain
Interests: pathology; diseases; sheep health management
Special Issues, Collections and Topics in MDPI journals
Dr. Aurora Ortín

E-Mail Website
Guest Editor
Departamento de Patología Animal, Facultad de Veterinaria, Instituto Agroalimentario de Aragón-IA2, Universidad de Zaragoza-CITA, C/Miguel Servet 177, 50013 Zaragoza, Spain
Interests: welfare and pathology of small ruminants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A wide variety of viruses can cause detrimental effects on the health and performance of small ruminants, leading to economic losses on the farms and adverse welfare consequences for the animals.  

In-depth knowledge of these viruses and the diseases they can be involved in is crucial for the implementation of effective control measures.

The aim of this Special Issue is to publish original research papers or reviews concerning viruses affecting small ruminants. We encourage you to share new information about this topic.

Dr. Delia Lacasta
Dr. Aurora Ortín
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sheep
  • goats
  • lambs
  • small ruminants
  • viruses

Published Papers (2 papers)

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Research

14 pages, 961 KiB  
Article
Use of a Local Anaesthetic/Antiseptic Formulation for the Treatment of Lambs Experimentally Infected with Orf Virus
by Delia Lacasta, Marina Ríos, Marta Ruiz de Arcaute, Aurora Ortín, Juan José Ramos, Sergio Villanueva-Saz, María Teresa Tejedor, Héctor Ruiz, Marta Borobia, Ramsés Reina, Alex Gómez, Teresa Navarro and Peter Andrew Windsor
Animals 2023, 13(18), 2962; https://doi.org/10.3390/ani13182962 - 19 Sep 2023
Cited by 2 | Viewed by 1114
Abstract
Contagious ecthyma is a highly transmissible eruptive viral disease of the skin and mucosa of sheep and goats distributed worldwide. The treatment of orf lesions is usually based on the use of antiseptics and antibiotics for the management of presumptive secondary infections, increasing [...] Read more.
Contagious ecthyma is a highly transmissible eruptive viral disease of the skin and mucosa of sheep and goats distributed worldwide. The treatment of orf lesions is usually based on the use of antiseptics and antibiotics for the management of presumptive secondary infections, increasing risks of antimicrobial resistance. The wound dressing formulation Tri-Solfen® (TS) containing two local anaesthetics (lignocaine and bupivacaine), adrenaline and an antiseptic (cetrimide) in a gel formulation has been demonstrated to reduce suffering and enhance recovery in cattle and buffalo with oral and skin lesions due to foot-and-mouth disease virus infection and reduced the orf viral load in lambs. In the present study, experimental infection with the orf virus was conducted in 50 newborn lambs and 25 animals were treated after the presence of the first lesions with TS and repeated three days later. Daily clinical examination, haematological, serological, biomolecular and post-mortem analyses were conducted during 34 days after treatment. Results indicated that treatment had no effect on weight gain and clinical progression of the lesions. It was determined that seroconversion after experimental infection occurs 34 days after infection and suggested that the deep basal epithelial location of the orf lesions may have prevented the therapy from having altered the clinical course. Full article
(This article belongs to the Special Issue The Pathway to Solutions: Diagnosing and Treating Viral Diseases of Small Ruminants)
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9 pages, 7293 KiB  
Article
Pathological Spectrum of Ovine Pulmonary Adenocarcinoma in Small Ruminants: A Focus on the Mixed Form
by Joaquín Ortega, Juan M. Corpa, Diego Castillo and Brian G. Murphy
Animals 2023, 13(18), 2828; https://doi.org/10.3390/ani13182828 - 06 Sep 2023
Cited by 1 | Viewed by 1393
Abstract
Ovine pulmonary adenocarcinoma (OPA) is a contagious respiratory tumor of small ruminants, manifesting in chronic weight loss and respiratory failure. Infection with the betaretrovirus jaagsiekte sheep retrovirus (JSRV) is the cause of OPA. Here, we describe the gross and microscopic features of twenty-six [...] Read more.
Ovine pulmonary adenocarcinoma (OPA) is a contagious respiratory tumor of small ruminants, manifesting in chronic weight loss and respiratory failure. Infection with the betaretrovirus jaagsiekte sheep retrovirus (JSRV) is the cause of OPA. Here, we describe the gross and microscopic features of twenty-six sheep and one goat with naturally occurring JSRV-associated OPA. All the animals included in this study had pulmonary lesions morphologically consistent with OPA, but the majority of the observed lesions demonstrated features of both the classical and the atypical form of OPA, and were, therefore, classified grossly as mixed. The gross lesions were located mainly in the cranial pulmonary lobes, were multifocal to coalescing, variable in number and size, flat to slightly raised, firm, and white to grey. Histologically, the cases were classified according to the predominant architectural patterns as lepidic, papillary, acinar, or mixed; the mixed histological pattern was the most prevalent. The aim of this study was to describe the gross and microscopic spectrum of OPA in naturally infected small ruminants from Spain. The mixed form of OPA is less commonly reported, and can be confused with other concurrent pulmonary pathologies (such as BALT hyperplasia in SRLV-associated pneumonia or lungworm granulomas). Full article
(This article belongs to the Special Issue The Pathway to Solutions: Diagnosing and Treating Viral Diseases of Small Ruminants)
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