Dear Colleagues,

Gastro-intestinal and liver helminths are a major health problem, particularly for grazing herbivores. The first Special Issue on the same topic did not cover all the fields of research in this area, driving the publication of this second Special Issue. We may expect that the use of pasture as a natural source of feed will be maintained or even increased due to the consumer expectations for naturalness. The use of available anthelmintics has proved efficient for decades, but resistance to anthelmintics has steadily increased in small ruminants and equids, and is nowadays also distributed in cattle. The stakeholders of husbandry then turned to alternative solutions such as breeding production animals for resistance, mostly against gastro-intestinal nematodes. The investigation for drugs based on new mechanisms is an avenue for the control of infection. The use of natural drugs derived from plants has also been promoted. The use of the new available drugs should be moderate and targeted to the animals in need of treatments if we want to avoid the appearance of resistance to these drugs. The management of pastures should be also included in control programs.

We are pleased to invite you to contribute this Special Issue searching for original and novel papers on the recent evolution of the prevalence of gastrointestinal and Fasciola infections, the ways to control them through an increase in host resistance, synthetic anthelmintics or natural substances, and the management of pastures.

This Special Issue aims to provide information on the recent findings in managing helminthiases in ruminants and equids.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

1. Resistance of host to GIN or Fasciola;
2. New mechanisms of drug action and control of GIN or Fasciola;
3. Kinds of drugs for control: both in vivo and vitro studies addressing the anthelmintic potential of bio-active compounds from natural source, as well as synthetic compounds;
4. Ways to use available drugs in a context of resistance and targeted selective treatments (TST);
5. Parasite control in the environment (pasture management, snail control, etc.);
6. Farmers’ vision of gastrointestinal nematode management.

We look forward to receiving your contributions.

Dr. Jacques Cabaret
Guest Editor

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• host resistance
• anthelmintics
• TST
• Fasciola
• gastrointestinal helminths