Microbial Genomics in Animal Sciences

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 1980

Special Issue Editor


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Guest Editor
Institut Pasteur de Montevideo, Montevideo, Uruguay
Interests: antimicrobial resistance; microbial pathogenicity; human, animal and environmental microbiome; computational microbiology; genomics

Special Issue Information

Dear Colleagues,

Thousands of bacteria, viruses and eukaryotic microbes associated with animal hosts are constantly being described and characterized by means of high-throughput sequencing technologies using both whole-genome and metagenomic approaches. These microbes can have diverse biological functions, from being beneficial to the host to causing disease and transmitting to other species or the environment. Accordingly, not only are animal microbes relevant in the livestock industry and wildlife conservation, but also, they may represent a threat to human and environmental health. This Special Issue plans to give an overview of the latest advancements in the application of genomic, metagenomic and bioinformatic approaches to investigate the biology of animal microbes, with particular focus on integrative studies that incorporate a one-health perspective.

Potential topics include, but are not limited to:

  • Antimicrobial resistance;
  • Livestock and wildlife microbiomes;
  • Population genomics of zoonotic bacteria and viruses;
  • Genomic analysis of animal microbes.

Dr. Gregorio Iraola
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

14 pages, 2853 KiB  
Article
Characterization of the Gut Microbiome in Healthy Dogs and Dogs with Diabetes Mellitus
by Tsz Ching Kwong, Eddie Chung Ting Chau, Mark Chi Ho Mak, Chi Tung Choy, Lee Tung Chan, Chun Keung Pang, Junwei Zhou, Phoebe Hoi Ching Poon, Yuqiong Guan, Stephen Kwok Wing Tsui, Shun Wan Chan, George Pak Heng Leung, William Chi Shing Tai and Yiu Wa Kwan
Animals 2023, 13(15), 2479; https://doi.org/10.3390/ani13152479 - 01 Aug 2023
Cited by 1 | Viewed by 1591
Abstract
With a close pathogenetic resemblance to human diabetes, canine Diabetes Mellitus, a chronic metabolic disease featuring abnormally high blood sugar levels, is increasing in prevalence worldwide. Unlike humans, canine glycemic control requires life-long insulin injections and dietary control in most cases, thereby jeopardizing [...] Read more.
With a close pathogenetic resemblance to human diabetes, canine Diabetes Mellitus, a chronic metabolic disease featuring abnormally high blood sugar levels, is increasing in prevalence worldwide. Unlike humans, canine glycemic control requires life-long insulin injections and dietary control in most cases, thereby jeopardizing diabetic dogs’ quality of life and increasing the difficulty of disease control. While many research studies have focused on elucidating the relationship between the canine gut microbiome and diseases, there is currently no research on the subject of diabetes mellitus in dogs. We hypothesized that the gut microbiome of canines with diabetes mellitus is different from that of healthy controls. Thus, we performed targeted 16S rRNA sequencing and comprehensive bioinformatic analysis to compare the gut microbiome profiles of 16 diabetic dogs with those of 32 healthy dogs. Clostridioides difficile, Phocaeicola plebeius, Lacrimispora indolis, and Butyricicoccus pullicaecorum were found to be enriched in diabetic dogs. A distinct shift towards carbohydrate degradation metabolic pathways was found to be differentially abundant in the diabetic subjects. Alteration of the co-occurrence network was also evident in the diabetic group. In conclusion, our study suggests that the gut microbial landscape differs in diabetic canines at the genera, species, functional, and network levels. These findings have significant implications for disease management, and thus warrant further research. Full article
(This article belongs to the Special Issue Microbial Genomics in Animal Sciences)
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