Application of Molecular Markers and Major Genes in the Genetic Improvement of Cattle

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 1681

Special Issue Editor


E-Mail Website
Guest Editor
Animal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju, Jeollabuk-do, Korea
Interests: genomic prediction (selection); GWAS, RNA-seq; multi-omics integration; climate change in animals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Cattle is a major livestock species that has been genetically improved by statistical breeding and molecular technologies such as genomic selection, next-generation sequencing, gene editing, etc. However, the livestock industry still faces challenging issues such as increasing demand for meat products, as well as GHGs (greenhouse gases) emissions and animal disease. Therefore, we launched the Special Issue ‘Application of Molecular Markers and Major Genes in the Genetic Improvement of Cattle’. These issues could provide insight into the application, effect and discovery of molecular markers and genes related with various phenotypes to livestock science and industry.

Dr. Jong-Eun Park
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cattle
  • genetic improvement
  • molecular markers
  • genes

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

11 pages, 1993 KiB  
Article
miR-183/96/182 Cluster Regulates the Development of Bovine Myoblasts through Targeting FoxO1
by Wenxiu Ru, Kunpeng Liu, Jiameng Yang, Jianyong Liu, Xinglei Qi, Bizhi Huang and Hong Chen
Animals 2022, 12(20), 2799; https://doi.org/10.3390/ani12202799 - 17 Oct 2022
Cited by 2 | Viewed by 1340
Abstract
Muscle development is an important factor affecting meat yield and quality and is coordinated by a variety of the myogenic genes and signaling pathways. Recent studies reported that miRNA, a class of highly conserved small noncoding RNA, is actively involved in regulating muscle [...] Read more.
Muscle development is an important factor affecting meat yield and quality and is coordinated by a variety of the myogenic genes and signaling pathways. Recent studies reported that miRNA, a class of highly conserved small noncoding RNA, is actively involved in regulating muscle development, but many miRNAs still need to be further explored. Here, we identified that the miR-183/96/182 cluster exhibited higher expression in bovine embryonic muscle; meanwhile, it widely existed in other organizations. Functionally, the results of the RT-qPCR, EdU, CCK8 and immunofluorescence assays demonstrated that the miR-183/96/182 cluster promoted proliferation and differentiation of bovine myoblast. Next, we found that the miR-183/96/182 cluster targeted FoxO1 and restrained its expression. Meanwhile, the expression of FoxO1 had a negative correlation with the expression of the miR-183/96/182 cluster during myoblast differentiation. In a word, our findings indicated that the miR-183/96/182 cluster serves as a positive regulator in the proliferation and differentiation of bovine myoblasts through suppressing the expression of FoxO1. Full article
Show Figures

Figure 1

Back to TopTop