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Rheumato, Volume 3, Issue 2 (June 2023) – 2 articles

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37 pages, 1795 KiB  
Systematic Review
Non-Multisystem Inflammatory Syndrome in Children—Postacute Sequelae of Paediatric COVID-19: Autoimmune or Autoinflammatory? A Systematic Review of the Reported Cases
by Antoine Fakhry AbdelMassih, Maram Hamed Hanafy, Maryam ElAhmady, Sylvia Kozman, Nourine Diab, Reem Husseiny, Ashrakat Deyab, Aalaa Mady, Alia Yasser, Amira R. AbdelHalim, Aya Mohyeldin, Aya Sayed Serour, Ayat AbdelGadir, Eslam Abdelaziz, Farida ElGhamry, Hana Amr, Karim Milad, Lamya Fouda, Mawada Hesham, Mina Adly Riad, Mohamed Aoun, Rana AbdelTawab, Rana Sayed, Salma ElSenbawy, Sara ElAhmady Abdelkhalek, Nada Gamal and Yasmin Omaradd Show full author list remove Hide full author list
Rheumato 2023, 3(2), 132-168; https://doi.org/10.3390/rheumato3020011 - 30 May 2023
Viewed by 2502
Abstract
Three years after its emergence, coronavirus disease 2019 (COVID-19) continues to be a leading cause of worldwide morbidity and mortality. This systematic review comprises relevant case reports that discuss non-multisystem inflammatory syndrome in children (non-MIS-C) and postacute sequalae of COVID-19 (PASC) in the [...] Read more.
Three years after its emergence, coronavirus disease 2019 (COVID-19) continues to be a leading cause of worldwide morbidity and mortality. This systematic review comprises relevant case reports that discuss non-multisystem inflammatory syndrome in children (non-MIS-C) and postacute sequalae of COVID-19 (PASC) in the paediatric population, also known as long COVID syndrome. The study aims to highlight the prevalent time interval between COVID-19 and the development of non-MIS-C post-infectious sequalae (PIS). Databases were searched for studies that met our inclusion and exclusion criteria. The final screening revealed an equal sex distribution where the commonest age intervals were school-age and adolescence, with 38% of the patients being older than six years. Interestingly, hospital admission during the course of COVID-19 was not a predictor of the subsequent PASC; forty-nine patients (44.9%) were hospitalized while sixty patients (55.1%) were not hospitalized. Moreover, the most predominant time interval between COVID-19 and the developing PASC was within 14 days from the start of COVID-19 infection (61%). These findings suggest a crucial link between COVID-19 and immune PIS in the paediatric population, especially those older than six years. Accordingly, follow-up and management are encouraged in case of unusual symptoms and signs following COVID-19 infection, regardless of the COVID-19 infection severity. Full article
(This article belongs to the Special Issue Post-COVID Rheumatic and Immune-Mediated Diseases)
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14 pages, 716 KiB  
Article
Periodontal Health as Perceived by Rheumatologists and Rheumatoid Arthritis Patients
by Natasha Proud, Grace Hughes, Cohen McCashney and Letícia Algarves Miranda
Rheumato 2023, 3(2), 118-131; https://doi.org/10.3390/rheumato3020010 - 21 Apr 2023
Cited by 1 | Viewed by 1223
Abstract
The aim of the present study is to assess the knowledge and attitudes towards periodontal health among rheumatologists and rheumatoid arthritis (RA) patients. Two questionnaires comprising questions on demographics, knowledge, and attitudes towards periodontal health were created via Qualtrics survey software. A link [...] Read more.
The aim of the present study is to assess the knowledge and attitudes towards periodontal health among rheumatologists and rheumatoid arthritis (RA) patients. Two questionnaires comprising questions on demographics, knowledge, and attitudes towards periodontal health were created via Qualtrics survey software. A link to the survey was sent via email to rheumatologists registered under the Australian Rheumatology Association (ARA) practising in Western Australia, and a separate survey was distributed to patients via Arthritis and Osteoporosis WA social media pages. Seven and 76 responses were received from rheumatologists and RA patients, respectively. Statistically significant results (p < 0.05) were found between the length of RA diagnosis and signs of periodontal disease, as well as the type of RA diagnosis and knowledge levels. Employed and retired participants attended the dentist more regularly, and a higher percentage believed that maintaining good oral hygiene is important for overall health. A significant correlation was found between patients who thought improving oral hygiene would impact their RA and whether they received periodontal treatment. No significant differences were found for rheumatologists; however, younger practitioners more frequently asked about their patients’ oral health and performed oral exams. There is a deficit in knowledge about the relationship between periodontal disease and RA among both rheumatoid patients and rheumatologists. The high prevalence of periodontitis and the two-way relationship between RA and periodontal disease would benefit from improved knowledge in relation to their association and could have significant benefits in their clinical and public health implications. Full article
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