(1′S)-1′-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion
Abstract
:1. Introduction
2. Results
2.1. Isolation and Identification of Phenylpropanoids 1–7 from the Rhizomes of A. galanga
2.2. Effects of Phenylpropanoids 1–7 on Glucose-Stimulated Insulin Secretion
2.3. Effects of AEA (3) on the Protein Expression of P-IRS-2, IRS-2, P-PI3K, PI3K, P-Akt (Ser473), Akt, and PDX-1
2.4. Effects of AEA (3) on α-Glucosidase Inhibitory Activity
3. Discussion
4. Materials and Methods
4.1. Isolation of Phenylpropanoids 1–7 from A. galanga
4.2. Cell Culture
4.3. Cell Viability Assay
4.4. GSIS Assay
4.5. Western Blot Analysis
4.6. Assay of α-Glucosidase Activity
4.7. Statistical Analysis
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Lee, D.; Son, S.-R.; Qi, Y.; Kang, K.S.; Jang, D.S. (1′S)-1′-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion. Plants 2023, 12, 579. https://doi.org/10.3390/plants12030579
Lee D, Son S-R, Qi Y, Kang KS, Jang DS. (1′S)-1′-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion. Plants. 2023; 12(3):579. https://doi.org/10.3390/plants12030579
Chicago/Turabian StyleLee, Dahae, So-Ri Son, Yutong Qi, Ki Sung Kang, and Dae Sik Jang. 2023. "(1′S)-1′-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion" Plants 12, no. 3: 579. https://doi.org/10.3390/plants12030579