Phytochemical Investigation and Biological Studies on Selected Searsia Species
, Masixole Makhaba 1,3, Ndikho Nako 1, Fanie Rautenbach 4, Jelili A. Badmus 4, Jeanine Marnewick 4, Ahmed A. Hussein 3,* and Wilfred T. Mabusela 1,*Round 1
Reviewer 1 Report
In the study "Phytochemical investigation and biological studies on selected Searsia species" , the authors studied the chemical structures of the isolated compounds from S. gluaca, S. Lucida and S. laevigata and antioxidant and alpha glucosidase assay. The study was interesting. However, the manuscript needs to be improved for publication in the Plants MDPI journal.
Comments
1) In Table 2 report Ferric ion reducing (FRAP) and Trolox equivalent antioxidant capacities (TEAC) of S. lucida, S. laevigata, and S. glauca extracts. Authors need to mention the statistical significance compared with the standard.
2 ) Mode of antidiabetic mechanism need to be discussed
3) Authors studied the isolated compounds using FTIR , HPLC, NMR...however, no graphical image / data found
4) The author should discuss about the ethnomedical importance and earlier studies conducted in Searsia glauca, Searsia Lucida, and Searsia laevigata
Author Response
Please see the attachment.
Author Response File: 
Author Response.docx
Reviewer 2 Report
The article entitled "Phytochemical investigation and biological studies on selected Searsia species" is very well written and could be published in Plants after a little revision. In line 255, the word "by" is redundant
In line 263 it is not said what the column was finally washed with: "... and washed with 100%." of what, solvent with higher polarity?
Author Response
Please see the attachment.
Author Response File: Author Response.docx
Round 2
Reviewer 1 Report
Dear editor,
The authors responsed to the queries point by point and manuscript could be accepted for possible publication.
