African American Females Are Less Metabolically Flexible Compared with Caucasian American Females following a Single High-Fat Meal: A Pilot Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Subject Characteristics
3.2. Lipid Oxidation and Metabolic Flexibility
3.3. Plasma Insulin and Glucose
3.4. Inflammation
3.5. Exploratory Correlative Analysis between Metabolic Flexibility, Insulin, Glucose and IL-8 Concentrations
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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CA Females | AA Females | t-Test p-Value | |
---|---|---|---|
Age (y) | 26.5 (1.5) | 25.6 (5.6) | p = 0.714 |
Weight (kg) | 70.1 (21.4) | 75.1 (15.8) | p = 0.534 |
BMI (kg/m2) | 25.7 (5.3) | 27.2 (6.0) | p = 0.535 |
SBP (mmHg) | 120.9 (11.8) | 117.8 (12.3) | p = 0.575 |
DBP (mmHg) | 75.5 (7.1) | 72.1 (12.2) | p = 0.433 |
Fasted blood glucose (mg/dL) | 100.2 (11.8) | 95.0 (18.4) | p = 0.431 |
Waist circumference (cm) | 33.5 (7.7) | 33.1 (5.0) | p = 0.894 |
Hip circumference (cm) | 39.1 (5.0) | 40.2 (6.3) | p = 0.632 |
Waist to hip (ratio) | 0.76 (0.1) | 0.76 (0.07) | p = 0.787 |
Body fat percentage | 25.0 (7.4) | 27.5 (9.7) | p = 0.492 |
Lean mass (kg) | 50.9 (11.2) | 53.3 (6.1) | p = 0.537 |
REE (kcals/d) | 1514.1 (272.4) | 1450.8 (107.2) | p = 0.480 |
HOMA-IR | 2.1 (2.6) | 2.1 (1.3) | p = 0.935 |
Matsuda’s ISI from meal challenge | 16.4 (16.2) | 14.7 (11.8) | p = 0.796 |
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Olenick, A.A.; Pearson, R.C.; Shaker, N.; Blankenship, M.M.; Tinius, R.A.; Winchester, L.J.; Oregon, E.; Maples, J.M. African American Females Are Less Metabolically Flexible Compared with Caucasian American Females following a Single High-Fat Meal: A Pilot Study. Int. J. Environ. Res. Public Health 2022, 19, 12913. https://doi.org/10.3390/ijerph191912913
Olenick AA, Pearson RC, Shaker N, Blankenship MM, Tinius RA, Winchester LJ, Oregon E, Maples JM. African American Females Are Less Metabolically Flexible Compared with Caucasian American Females following a Single High-Fat Meal: A Pilot Study. International Journal of Environmental Research and Public Health. 2022; 19(19):12913. https://doi.org/10.3390/ijerph191912913
Chicago/Turabian StyleOlenick, Alyssa A., Regis C. Pearson, Nuha Shaker, Maire M. Blankenship, Rachel A. Tinius, Lee J. Winchester, Evie Oregon, and Jill M. Maples. 2022. "African American Females Are Less Metabolically Flexible Compared with Caucasian American Females following a Single High-Fat Meal: A Pilot Study" International Journal of Environmental Research and Public Health 19, no. 19: 12913. https://doi.org/10.3390/ijerph191912913