Next Article in Journal
Regulated Assembly of the Mitotic Spindle: A Perspective from Two Ends
Previous Article in Journal
Genomes and Genome Projects of Protozoan Parasites
 
 
Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Impact of Transgenic Technologies on Functional Genomics

by
Cooduvalli S. Shashikant
1,* and
Frank H. Ruddle
2
1
Department Dairy and Animal Science, College of Agricultural Sciences, 324 Henning, University Park, PA 16802, USA
2
Department of MCDB and Genetics, Yale University, New Haven, CT 06511, USA
*
Author to whom correspondence should be addressed.
Curr. Issues Mol. Biol. 2003, 5(3), 75-98; https://doi.org/10.21775/cimb.005.075
Submission received: 9 March 2003 / Accepted: 14 May 2003 / Published: 1 July 2003

Abstract

Gene transfer technologies in mammals are the focus of renewed interest owing to the recent emphasis on analyzing gene function in the postgenomic era. Three important developments in this area include transgenics, gene targeting and nuclear transfer or animal cloning. These technological innovations have enhanced our ability to analyze gene function at the level of the whole organism and have provided the means to modify gene expression. This review discusses the origins and current status of transgenic technologies. Various applications and technologies including chromosome engineering, stem cells, gene traps and modification of livestock are presented. The impact of mouse technologies and genomics on functional analyses is also discussed.

Share and Cite

MDPI and ACS Style

Shashikant, C.S.; Ruddle, F.H. Impact of Transgenic Technologies on Functional Genomics. Curr. Issues Mol. Biol. 2003, 5, 75-98. https://doi.org/10.21775/cimb.005.075

AMA Style

Shashikant CS, Ruddle FH. Impact of Transgenic Technologies on Functional Genomics. Current Issues in Molecular Biology. 2003; 5(3):75-98. https://doi.org/10.21775/cimb.005.075

Chicago/Turabian Style

Shashikant, Cooduvalli S., and Frank H. Ruddle. 2003. "Impact of Transgenic Technologies on Functional Genomics" Current Issues in Molecular Biology 5, no. 3: 75-98. https://doi.org/10.21775/cimb.005.075

Article Metrics

Back to TopTop