Topic Editors

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy “Grigore T. Popa” Iasi, 16 University Street, 700115 Iasi, Romania
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 16 University Street, 700115 Iasi, Romania

Challenges and Opportunities in Drug Delivery Research

Abstract submission deadline
31 December 2024
Manuscript submission deadline
31 March 2025
Viewed by
980

Topic Information

Dear Colleagues,

The topic "Challenges and Opportunities in Drug Delivery Research" encompasses innovative drug delivery and release science research with significant implications in medical fields such as cancer therapy, neurology, and cardiovascular medicine. This pioneering research aims to transform treatment methods by developing advanced drug delivery systems that improve precision, reduce side effects, and enhance patient outcomes. The scope extends to gene therapies, personalized medicine, and novel approaches addressing complex health challenges, potentially reshaping healthcare by providing tailored and effective solutions for various diseases and conditions.

Key focus areas involve a mechanistic comprehension of drug delivery systems based on biological and physicochemical principles and mathematical modeling, predictive analytics, drug delivery systems, and cellular interactions tailored for particular therapeutic objectives.

Potential topics of interest for discussion cover various drug delivery technologies, nanomedicine, different entry pathways into the human body, technology evaluations, drug delivery strategies, precise delivery and targeting at various levels and disease indications, and preclinical and clinical findings data related to drug delivery systems. Additionally, in-depth discussions could be extended to detailed explorations of the methods involved in delivering and releasing genes, vaccines, and antibodies.

Prof. Dr. Lenuta Profire
Dr. Ioana Mirela Vasincu
Topic Editors

Keywords

  • drug delivery technologies
  • release profile
  • nanotechnology
  • smart drug delivery
  • targeted delivery

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Current Issues in Molecular Biology
cimb
3.1 2.4 1999 13.5 Days CHF 2200 Submit
Molecules
molecules
4.6 6.7 1996 14.6 Days CHF 2700 Submit
Pharmaceuticals
pharmaceuticals
4.6 4.7 2004 14.6 Days CHF 2900 Submit
Pharmaceutics
pharmaceutics
5.4 6.9 2009 14.2 Days CHF 2900 Submit
Scientia Pharmaceutica
scipharm
2.5 6.4 1930 22.7 Days CHF 1000 Submit

Preprints.org is a multidiscipline platform providing preprint service that is dedicated to sharing your research from the start and empowering your research journey.

MDPI Topics is cooperating with Preprints.org and has built a direct connection between MDPI journals and Preprints.org. Authors are encouraged to enjoy the benefits by posting a preprint at Preprints.org prior to publication:

  1. Immediately share your ideas ahead of publication and establish your research priority;
  2. Protect your idea from being stolen with this time-stamped preprint article;
  3. Enhance the exposure and impact of your research;
  4. Receive feedback from your peers in advance;
  5. Have it indexed in Web of Science (Preprint Citation Index), Google Scholar, Crossref, SHARE, PrePubMed, Scilit and Europe PMC.

Published Papers (1 paper)

Order results
Result details
Journals
Select all
Export citation of selected articles as:
14 pages, 12746 KiB  
Article
Adenosine Encapsulation and Characterization through Layer-by-Layer Assembly of Hydroxypropyl-β-Cyclodextrin and Whey Protein Isolate as Wall Materials
by Yudie Jin and Suning Zhang
Molecules 2024, 29(9), 2046; https://doi.org/10.3390/molecules29092046 - 29 Apr 2024
Viewed by 611
Abstract
Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-β-cyclodextrin as the inner wall and whey protein isolate as the outer wall, to encapsulate adenosine within the core [...] Read more.
Adenosine, as a water-soluble active substance, has various pharmacological effects. This study proposes a layer-by-layer assembly method of composite wall materials, using hydroxypropyl-β-cyclodextrin as the inner wall and whey protein isolate as the outer wall, to encapsulate adenosine within the core material, aiming to enhance adenosine microcapsules’ stability through intermolecular interactions. By combining isothermal titration calorimetry with molecular modeling analysis, it was determined that the core material and the inner wall and the inner wall and the outer wall interact through intermolecular forces. Adenosine and hydroxypropyl-β-cyclodextrin form an optimal 1:1 complex through hydrophobic interactions, while hydroxypropyl-β-cyclodextrin and whey protein isolate interact through hydrogen bonds. The embedding rate of AD/Hp-β-CD/WPI microcapsules was 36.80%, and the 24 h retention rate under the release behavior test was 76.09%. The method of preparing adenosine microcapsules using composite wall materials is environmentally friendly and shows broad application prospects in storage and delivery systems with sustained release properties. Full article
(This article belongs to the Topic Challenges and Opportunities in Drug Delivery Research)
Show Figures

Graphical abstract

Back to TopTop