Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.0
7.8
Journals
Vaccines
Special Issues
2nd Edition of Poultry Vaccines
share announcement

2nd Edition of Poultry Vaccines

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Veterinary Vaccines".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2530

Special Issue Editors

Dr. Caterina Lupini

E-Mail Website
Guest Editor
Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy
Interests: avian viral diseases; vaccines; vaccine development; avian respiratory diseases; avian viral immunosuppressive diseases
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Elena Catelli

E-Mail Website
Guest Editor
Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy
Interests: vaccines; vaccine development; marek's disease; avian metapneumovirus; avian coronavirus; infectious bursal disease; newcastle disease; avian influenza; avian viral respiratory diseases; avian immunosuppressive diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This is the 2nd special issue of “Poultry Vaccines”. 

In this Special Issue, we still invite original research and review papers that address recent advances in the field of poultry vaccines either for viral, bacterial and parasitic diseases. Topics of interest include but are not limited to: poultry vaccine basic science, manufacturing, technology, safety, and efficacy. Both experimental or field animal trials are welcomed. Specific topics may include diagnostic strategies to differentiate infected from vaccinated animals, identification of vaccine molecular markers, engineered vaccine development (e.g., vectored vaccines) and novel vaccine delivery tools.  

Dr. Caterina Lupini
Prof. Dr. Elena Catelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • poultry vaccines
  • avian diseases
  • vaccine basic science
  • manufacturing
  • technology
  • safety
  • efficacy
  • engineered vaccine
  • delivery tools

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

17 pages, 5376 KiB  
Article
Effects of G and SH Truncation on the Replication, Virulence, and Immunogenicity of Avian Metapneumovirus
by Seung-Min Hong, Eun-Jin Ha, Ho-Won Kim, Seung-Ji Kim, Sun-Min Ahn, Se-Hee An, Gun Kim, Suji Kim, Hyuk-Joon Kwon and Kang-Seuk Choi
Vaccines 2024, 12(1), 106; https://doi.org/10.3390/vaccines12010106 - 21 Jan 2024
Viewed by 949
Abstract
Four mutants varying the length of the G and SH genes, including a G-truncated mutant (ΔG) and three G/SH-truncated mutants (ΔSH/G-1, ΔSH/G-2, and ΔSH/G-3), were generated via serially passaging the avian metapneumovirus strain SNU21004 into the cell lines Vero E6 and DF-1 and [...] Read more.
Four mutants varying the length of the G and SH genes, including a G-truncated mutant (ΔG) and three G/SH-truncated mutants (ΔSH/G-1, ΔSH/G-2, and ΔSH/G-3), were generated via serially passaging the avian metapneumovirus strain SNU21004 into the cell lines Vero E6 and DF-1 and into embryonated chicken eggs. The mutant ΔG particles resembled parental virus particles except for the variance in the density of their surface projections. G and G/SH truncation significantly affected the viral replication in chickens’ tracheal ring culture and in infected chickens but not in the Vero E6 cells. In experimentally infected chickens, mutant ΔG resulted in the restriction of viral replication and the attenuation of the virulence. The mutants ΔG and ΔSH/G-1 upregulated three interleukins (IL-6, IL-12, and IL-18) and three interferons (IFNα, IFNβ, and IFNγ) in infected chickens. In addition, the expression levels of innate immunity-related genes such as Mda5, Rig-I, and Lgp2, in BALB/c mice were also upregulated when compared to the parental virus. Immunologically, the mutant ΔG induced a strong, delayed humoral immune response, while the mutant ΔSH/G-1 induced no humoral immune response. Our findings indicate the potential of the mutant ΔG but not the mutant ΔSH/G-1 as a live attenuated vaccine candidate. Full article
(This article belongs to the Special Issue 2nd Edition of Poultry Vaccines)
►▼ Show Figures

Figure 1

19 pages, 11881 KiB  
Article
Superior Efficacy of Apathogenic Genotype I (V4) over Lentogenic Genotype II (LaSota) Live Vaccines against Newcastle Disease Virus Genotype VII.1.1 in Pathogen-Associated Molecular Pattern-H9N2 Vaccinated Broiler Chickens
by Ahmed Elbestawy, Hany Ellakany, Mahmoud Sedeik, Ahmed Gado, Mervat Abdel-Latif, Ahmed Noreldin, Ahmed Orabi, Ismail Radwan and Wafaa Abd El-Ghany
Vaccines 2023, 11(11), 1638; https://doi.org/10.3390/vaccines11111638 - 25 Oct 2023
Cited by 1 | Viewed by 1134
Abstract
A comparison of the efficacy of apathogenic genotype I (V4) and lentogenic genotype II (LaSota) strains of live Newcastle disease virus (NDV) vaccines was performed following vaccination with pathogen-associated molecular pattern (PAMP) H9N2 avian influenza vaccine and challenge with velogenic NDV genotype VII.1.1 [...] Read more.
A comparison of the efficacy of apathogenic genotype I (V4) and lentogenic genotype II (LaSota) strains of live Newcastle disease virus (NDV) vaccines was performed following vaccination with pathogen-associated molecular pattern (PAMP) H9N2 avian influenza vaccine and challenge with velogenic NDV genotype VII.1.1 (vNDV-VII.1.1). Eight groups (Gs) of day-old chicks were used (n = 25). Groups 1–4 received a single dose of PAMP-H9N2 subcutaneously, while Gs (1, 5) and (2, 6) received eye drops of V4 and LaSota, respectively, as two doses. All Gs, except for 4 and 8, were intramuscularly challenged with vNDV-VII.1.1 at 28 days of age. No signs were detected in Gs 1, 5, 4, and 8. The mortality rates were 0% in Gs 1, 4, 5, and 8; 40% in G2; 46.66% in G6; and 100% in Gs 3 and 7. Lesions were recorded as minimal in Gs 1 and 5, but mild to moderate in Gs 2 and 6. The lowest significant viral shedding was detected in Gs 1, 2, and 5. In conclusion, two successive vaccinations of broilers with a live V4 NDV vaccine provided higher protection against vNDV-VII.1.1 challenge than LaSota. PAMP-H9N2 with live NDV vaccines induced more protection than the live vaccine alone. Full article
(This article belongs to the Special Issue 2nd Edition of Poultry Vaccines)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop