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Colorectal Cancer Surgery
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Colorectal Cancer Surgery

A special issue of Surgeries (ISSN 2673-4095).

Deadline for manuscript submissions: closed (20 January 2024) | Viewed by 3089

Special Issue Editor

Dr. Peter C. Ambe

E-Mail Website
Guest Editor
Department of General Surgery, Visceral Surgery and Coloproctology, Vinzenz-Pallotti-Hospital Bensberg, Vinzenz-Pallotti-Str. 20-24, 51429 Bensberg, Germany
Interests: oncologic surgery; minimally invasive surgery; colorectal surgery; colorectal cancer

Special Issue Information

Dear Colleagues,

As colorectal and oncologic surgeons, we are constantly faced with challenging cases in both the elective and emergency setting. Archiving optimal oncologic results without compromising the quality of life constitutes the most important primary end point in the management of patients with colorectal cancer.

This Special Issue is focused on colorectal surgery. We will be accepting high-quality research papers on all aspects of colorectal cancer. You are welcome to submit manuscripts on relevant topics including preoperative rehabilitation, selective bowel decontamination, the role of minimally invasive access, robotics in colorectal surgery, real-time vascular study (ICG, hyperspectral imaging, etc.), anastomosis techniques (single stapling, double stapling, hand-sown), techniques of prevention staplerline intersection, the need of fecal diversion, the role of Ghost-Ileostoma (virtual ileostoma), transanal bowel decompression, ERAS, “wait and watch” strategy following chemoradiation of rectal cancer, tumor-markers, the role of surgery in the metastatic setting, etc. to this Special Issue.

Submitted manuscripts will be screened for eligibility, and suitable manuscripts will formally undergo a rigorous peer-review process. All accepted manuscripts will be published in an open access format.

I hereby invite you, as recognized experts in the management of colorectal cancer, to submit your work to this Special Issue.

I look forward to receiving your expert manuscripts.

Dr. Peter C. Ambe
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Surgeries is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • patient's safety
  • colorectal surgery
  • complications
  • anastomosis
  • prerehabilitation
  • selected bowel decontamination
  • fecal deviation
  • real-time vascular study
  • minimally invasive access
  • perioperative management

Published Papers (2 papers)

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Review

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7 pages, 251 KiB  
Review
Risk of Metachronous Colorectal Cancer in Lynch Syndrome: Who Needs an Extended Resection?
by Johannes Doerner
Surgeries 2022, 3(3), 185-191; https://doi.org/10.3390/surgeries3030020 - 4 Jul 2022
Cited by 1 | Viewed by 1801
Abstract
Lynch syndrome (LS) is the most common genetic condition associated with early-onset colorectal cancer. It is inherited in an autosomal dominant fashion. The increased cancer risk is due to a germline mutation in one of the mismatch repair (MMR) genes (MLH1, MSH2, MSH6, [...] Read more.
Lynch syndrome (LS) is the most common genetic condition associated with early-onset colorectal cancer. It is inherited in an autosomal dominant fashion. The increased cancer risk is due to a germline mutation in one of the mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) or the EPCAM gene. This leads to a deficient DNA mismatch repair mechanism, resulting in the accumulation of nucleotide changes and microsatellite instability, providing phenotypical evidence that MMR is not functioning normally. LS is associated with a high risk of early-onset colorectal cancer and recurrence. Thus, when undergoing surgery for primary colorectal cancer, extended resection should be discussed with the patient. This review provides an overview of current surgical risk-reducing strategies in LS-associated colorectal cancer. Surgical treatment for LS carriers with colorectal cancer needs to be highly individualized, based on patient and disease characteristics. Strategies are presented to guide decision making in pathologic MMR gene mutation carriers undergoing surgery for colorectal cancer. Full article
(This article belongs to the Special Issue Colorectal Cancer Surgery)

Other

Jump to: Review

11 pages, 251 KiB  
Protocol
A Comparison between Open and Minimally Invasive Right Hemicolectomies in Patients with Locally Advanced UICC Stage III Colon Cancer: A Protocol for a Systematic Review and an Individual Patient Data Meta-Analysis
by Jule Reitz, Simon Lindner, Stefan Benz, Guido Schwarzer, Svetlana Hetjens, Maurizio Grilli, Christoph Reissfelder, Steffen Seyfried and Florian Herrle
Surgeries 2023, 4(4), 706-716; https://doi.org/10.3390/surgeries4040066 - 15 Dec 2023
Viewed by 651
Abstract
Despite the development of new technologies and multimodal therapies, improving the prognosis of patients with UICC stage III right colon adenocarcinoma remains challenging. Several randomized controlled trials have shown the oncological non-inferiority of minimally invasive surgery compared to open surgery for colon cancer [...] Read more.
Despite the development of new technologies and multimodal therapies, improving the prognosis of patients with UICC stage III right colon adenocarcinoma remains challenging. Several randomized controlled trials have shown the oncological non-inferiority of minimally invasive surgery compared to open surgery for colon cancer patients. However, for UICC stage III patients, carrying the highest risk for local recurrence and the worst survival, the evidence remains inconclusive. The aim of this systematic review and individual patient data meta-analysis is to improve the scarce evidence regarding minimally invasive surgery for this subgroup of patients. Data from adult patients with pathologically UICC stage III right adenocarcinoma of the colon will be included. The intervention to be assessed is the minimally invasive right hemicolectomy in comparison with the open procedure. The primary outcome will be the 5-year overall survival. Secondary outcomes will include further long-term outcomes, such as disease-free survival, short term, and histological outcomes. Only randomized controlled trials and quasi-randomized controlled clinical trials will be included. The literature search will be conducted in the following databases: PubMed, CINAHL, Cochrane Trials, ClinicalTrials.gov, and Web of Science. The review will be performed using the Cochrane methodology including GRADE tools. The findings of this meta-analysis will be important for choosing optimal treatment pathways and tailoring of surgical therapy in patients with locally advanced UICC stage III right colon cancer. Full article
(This article belongs to the Special Issue Colorectal Cancer Surgery)
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