Review Papers of Separations

Dear Colleagues,

The development of science and technology has given humanity an uncountable number of benefits, and separations is a field that has greatly contributed to this development. The open access journal Separations covers separation and purification science and technology in all areas of chemical, biological, and physical science, as well as separation performance. It publishes original research papers, reviews, and short communications.

This Topical Collection is designed to gather review papers in the areas of separation and purification. We kindly invite and encourage all research groups to make contributions to this Topical Collection.

Prof. Dr. Frank L. Dorman
Dr. Gautam Sethi
Collection Editors

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• separations
• chromatographic
• sample preparation
• purification technology

Title: Chalcones, Versatile Intermediates in Heterocyclic Synthesis
Authors: Yogeesha N Nayak1, Mariya Sabu1, Basappa2, Gautam Sethi3,*, Santosh L Gaonkar1,*,
Affiliation: 1. Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Edu- cation, Manipal, 576104, Karnataka, India. 2. Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore-570006, India. 3. Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singa- pore, Singapore 117600
Abstract: Chalcones are a fascinating and well-studied group of organic molecules. Synthesis of chalcones has been one of the important areas of organic synthesis over the last few decades because of their im- mense therapeutic and excellent photo-physical properties. Furthermore, these chalcone derivatives can be utilised to make a variety of heterocyclic compounds especially five and six membered het- erocycles. Heterocyclic compounds have a long history in chemistry, primarily in pharmaceuticals. However, the synthesis of certain heterocyclic molecules remains difficult, requires multistep pro- cesses with few possible intermediates. Chalcones could be considered as one of the most useful, easily available intermediate in heterocyclic synthesis. Herein, the synthesis of various potential heterocyclic compounds using chalcones as intermediate is elaborated. This review shows the un- tapped potential of chalcones in organic synthesis. Also, it will assist the chemist in designing new heterocycles by adopting these strategies.