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Cyto-Histopathogical Correlations in Pathology Diagnostics
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Cyto-Histopathogical Correlations in Pathology Diagnostics

A special issue of Reports (ISSN 2571-841X).

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 7129

Special Issue Editor

Dr. Ivana Kholová

E-Mail Website
Guest Editor
1. Head of Cytopathology, Fimlab Laboratories, 33100 Tampere, Finland
2. Faculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland
Interests: cytology; FNA; HPV primary screening; cardiovascular pathology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Cyto-histological correlation means, by definition, comparison of cytological and histological diagnoses from the same lesion. It is a measure of quality assurance in the laboratory. It is a part of laboratory routine diagnostics on a case-based level and as a parameter series-based quality assurance.

Both series and cases are invited for a combined Special Issue in Diagnostics (series) and Reports (case reports). Covers of both gynecological and non-gynecological cytology, including fine needle aspirations, effusions, and brushing, are welcomed. The diagnostic issues and possible pitfalls should be discussed. Aspects of lesions imaging, sampling, processing, and staining can be highlighted in the cyto-histological correlation.

You may choose our Joint Special Issue in Diagnostics.

Dr. Ivana Kholová
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Reports is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cytology
  • cytopathology
  • cytological-histological correlation

Related Special Issue

Published Papers (2 papers)

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7 pages, 1565 KiB  
Case Report
Tear Liquid for Predictive Diagnosis of Alzheimer’s Disease
by Salvatore Del Prete, Daniela Marasco, Rosalaura Sabetta, Antonio Del Prete, Federica Zito Marino, Renato Franco, Salvatore Troisi, Mario Troisi and Gilda Cennamo
Reports 2021, 4(3), 26; https://doi.org/10.3390/reports4030026 - 25 Aug 2021
Cited by 3 | Viewed by 3667
Abstract
The common approach of the diagnosis of Alzheimer’s Disease (AD) is made with an analysis of the cerebrospinal fluid or the study of retinal fundus and the plaques formation through optical corneal tomography (OCT), or more simply with a fundus camera. Tears analysis [...] Read more.
The common approach of the diagnosis of Alzheimer’s Disease (AD) is made with an analysis of the cerebrospinal fluid or the study of retinal fundus and the plaques formation through optical corneal tomography (OCT), or more simply with a fundus camera. Tears analysis is widely discussed in literature as an essential method to describe molecular and biochemical alterations in different diseases. The aim of our study was the identification with immunocytochemistry of Amyloid Beta-42 in tears from patients with or without familiarity for Alzheimer Disease, in order to make the diagnosis earlier and more accessible compared to other invasive methods. Our study was performed on tears from three phenotypically healthy subjects: two of them were Caucasian with Alzheimer familiarity (48 and 55 years old) and the other one was Asian without Alzheimer familiarity (45 years old) and affected by an adenoviral keratoconjunctivitis at the moment of withdrawal. Tear samples were collected from eye fornix and were examinated by immunocytochemistry (ICC) assay using anti-Amyloid Beta X-42 antibody. Two out of three tears samples showed positive Amyloid Beta-42. Considering that our patients were phenotypically healthy, the identification of Amyloid Beta-42 by ICC could be a candidable method to make the diagnosis of the disease earlier and more accessible and available then other current and invasive methods and it could be a candidate for a screening method too. Full article
(This article belongs to the Special Issue Cyto-Histopathogical Correlations in Pathology Diagnostics)
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6 pages, 1048 KiB  
Case Report
The Role of Cytology in the Diagnosis of Metastatic Hepatocellular Carcinoma
by Jui-Chung Wang, Jui-Ting Hu and Chih-Yu Hsu
Reports 2021, 4(3), 20; https://doi.org/10.3390/reports4030020 - 30 Jun 2021
Viewed by 2736
Abstract
The diagnosis of primary hepatocellular carcinoma (HCC) in high risk patients, such as those with chronic hepatitis B or C with/without cirrhosis of the liver, can be made with relevant image studies alone; however, morphologic confirmation by cytology or histopathology is essential to [...] Read more.
The diagnosis of primary hepatocellular carcinoma (HCC) in high risk patients, such as those with chronic hepatitis B or C with/without cirrhosis of the liver, can be made with relevant image studies alone; however, morphologic confirmation by cytology or histopathology is essential to the diagnosis of metastatic HCC because the treatment of the latter differs from that of primary extrahepatic malignancy. Although both cytology and histopathology are important tools in the diagnosis of malignancy, histopathology almost always plays a confirmatory and pivotal role, and also a gold standard in cyto-histological correlation. We present two patients of metastatic HCC to rare sites; endobronchus in one, and neck lymph nodes, face and the abdominal wall in the other. Repeated bronchial biopsy in the first patient and excisional biopsy from the metastatic sites of the second patient failed to make a conclusive diagnosis of metastatic HCC. However, bronchial brushing in the first patient and fine needle aspiration cytology from the respective metastatic sites of the second patient consistently showed characteristic HCC features and provided clinicians with the rationale for ongoing treatment. The diagnostic issues and possible pitfalls are discussed. Cytology and histopathology appear equipollent; sometimes cytology can play a diagnostic role when histopathology fails its expected role in this scenario. Full article
(This article belongs to the Special Issue Cyto-Histopathogical Correlations in Pathology Diagnostics)
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