Biophotonics in Diagnostic Applications

Dear Colleagues,

Diagnostic biophotonics is used to detect diseases in their initial stages before actual medical symptoms occur in patients. By using optics, diagnostic biophotonics provides several advantages of sensing and imaging at the molecular level and also collects multidimensional data for evaluation. Technologies based on light are generally contact-free with a smaller effect on integrity of living subjects and, consequently, can easily be applied in situ.

• Optical tagging: Proteins, cells, nucleic acids, and tissues are tagged with optical tags and their incandescence or fluorescence is measured; further, according to the pathological or physiological situation, the changes are analyzed for the detection of genetic, infective, and other diseases;
• Visualization of complex structures: Advanced optical technologies have enhanced imaging of vasculature, retinal structures, optic nerve, and other ocular structures to provide precise diagnosis of ocular diseases. By observing the modifications occurring in microstructures, the diagnosis of common vascular disorders as well as metabolic and degenerative diseases is enabled;
• Functional diagnosis: Sophisticated optical technologies involving lasers and photonic and biophotonic applications in medicine provide assistance in observing and identifying cellular biochemistry and their functions, blood oxygenation level and flow, organ integrity, and the functional characteristics of tissues;
• Optical endoscopes: In medical applications, the combination of optical fibers and endoscopes is used for less invasive imaging and surgery of internal organs. Laser light with high-level intensity is delivered using an optical fiber to an inner region of the body, for instance, to eradicate tumors.

Submitted papers may report new results or offer a review. In the former case, your submission will not prevent you from publishing similar results in other journals, but the presentation should emphasize specific aspects that will make it different from related publications. A review may be either a comprehensive or a more limited article. Relatively brief reviews focused on recent findings of the authors are acceptable. Submissions will have to pass peer review, according to the commonly accepted procedure.

Dr. Samarendra Mohanty
Dr. Hrebesh M. Subhash
Dr. Mikhail Kirillin
Guest Editors

Manuscript Submission Information

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