Emerging Trends in Multi-photon Microscopy

Dear Colleagues,

Multi-photon microscopy has proven to be an essential tool in life sciences thanks to its capability of optical sectioning and deeper penetration into the tissue, allowing for better in vivo imaging. Live animal imaging is highly informative, especially for the investigation of complex biological or pathophysiological phenomena that cannot be properly modeled outside living organisms. Advances in multi-photon microscopy are continuously expanding our capabilities in biomedical research. There is a spectrum of newly developing techniques to optimize imaging parameters like penetration, resolution, field of view and speed. There has also been progress in the integration of multi-photon microscopy with other imaging modalities, optogenetic techniques, and electrophysiology, and the recent introduction of portable/wearable multi-photon microscopes is becoming beneficial for especially long-duration behavioral investigations in animals’ natural contexts. Additionally, the growing library of fluorophores and genetically modified animals complement technological advances in MP microscopy towards exciting scientific achievements.

This Special Issue aims to introduce the reader to technological advances in multi-photon microscopy from a multidisciplinary approach. We are seeking original research articles, letters, and review articles in the area. Research areas may include (but are not limited to) the following: engineering advances in multi-photon microscopy, use of multi-photon microscopy in life sciences, in vivo animal imaging with multi-photon microscopy, multi-photon microscopy use in neuroscience, novel fluorescent probes suitable for multi-photon microscopy, advances in analysis of multi-photon microscopy data.

We look forward to receiving your contributions.

Dr. Kıvılcım Kılıç
Dr. Şefik Evren Erdener
Guest Editors

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• microscopy
• multi-photon
• imaging
• life sciences
• in vivo
• neuroscience