Recent Advances in Antifungal Drugs 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 230
Special Issue Editors
Interests: antifungal agents; biofilms; fungal-host interaction; nanotechonology
Special Issues, Collections and Topics in MDPI journals
Interests: drug design; metallophores; antifungal agents; antibiofilm compounds
Special Issues, Collections and Topics in MDPI journals
2. Mycology Department, Adolfo Lutz Institute Center for Disease Control Secretary of Health, Sao Paulo 01246-000, SP, Brazil
Interests: antifungal agents; fungal infections; yeasts; molds
Special Issues, Collections and Topics in MDPI journals
Interests: antifungal agents, biofilms, fungal-host interaction, nanotechonology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The arsenal of antifungal agents against fungal diseases is limited. Furthermore, most treatments are associated with side effects, drug interactions, harmful risks for pregnant women, or fungal resistance.
The high burden and increasing prevalence of both invasive and superficial fungal infections, associated with biofilm formation, toxicity, interactions related to current antifungals, as well as increased resistance, require the development of new antifungals—preferably with a new form of action. Additionally, the availability of oral alternatives or mode drug use would allow outpatient treatment, resulting in greater patient comfort and therapy adherence. Besides, when needed due to immunosuppression, associated therapies should also focus on further research.
Antifungals are clinically available to treat fungal infections, and primarily target ergosterol in the fungal cell membrane or 1,3-β-D-glucan in the fungal cell wall. These classes include polyenes, triazoles, and echinocandins. Although the newer antifungals and the improved formulations of others have advanced, our ability to treat patients with fungal infections is often limited by toxicity, drug interactions, and the need for intravenous administration in the case of systemic mycoses.
Therefore, this Special Issue intends to receive manuscripts that present advances in antifungals, new targets, new formulations that utilize novel delivery systems to enhance treatment efficacy and compliance, and new strategies to treat fungal infections.
Prof. Dr. Maria José Soares Mendes Giannini
Dr. Luigi Scipione
Dr. Marcia S.C. Melhem
Dr. Ana Marisa Fusco Almeida
Guest Editors
Manuscript Submission Information
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Keywords
- antifungal drugs
- resistance
- biofilms resistance
- new targets
- invasive fungal infections
- superficial infections
- pipeline
- new formulations
- treatment
Related Special Issue
- Recent Advances in Antifungal Drugs in Pharmaceutics (12 articles)
