Special Issue "Pharmacokinetics and Clinical Pharmacology of Biological Drugs"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Clinical Pharmaceutics".

Deadline for manuscript submissions: 30 October 2023 | Viewed by 118

Special Issue Editors

Department of Pharmaceutics, University of Florida College of Pharmacy, Gainesville, FL 32610, USA
Interests: pharmacokinetics and clinical pharmacology
Department of Obstetrics, Gynecology & Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Interests: in vitro/in vivo ADME; drug-drug interactions; PBPK modeling
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biological drugs, also commonly known as biologics, are complex products derived from living organisms or cells. They are made using biotechnology methods and contain active substances that are typically large, complex molecules such as proteins, peptides, or nucleic acids. The use of biological drugs has grown in the past two decades to treat a wide range of diseases, including cancer, autoimmune disorders, and infectious diseases. Pharmacokinetic (PK) and pharmacodynamic (PD) properties play an important role in the consideration of these biologics for designing the dosage regimen, bio-similarity, and/or interchangeability of biological drugs. The pharmacokinetic properties of biologics, including monoclonal antibodies (mAbs) and other therapeutic proteins, can be quite different from small molecule drugs in different aspects, which makes the PK/PD model development more challenging and requires extra efforts to understand their ADME.

This Special Issue aims to invite researchers to share their research work demonstrating the pharmacokinetics and metabolism of biologics. This Special Issue will also cover broad interests in wielding diverse drug delivery systems to achieve the PK/PD optimization of biological drugs. This Special Issue also welcomes review articles concerning the clinical pharmacology of biologicals from experts.

We look forward to receiving your contributions.

Dr. Kanumuri Siva Rama Raju
Dr. Guru R. Valicherla
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • pharmacokinetics and metabolism
  • biologicals
  • pharmacokinetics and pharmacodynamic studies
  • bioavailability
  • drug delivery of biologics

Published Papers

This special issue is now open for submission.
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