Population Pharmacokinetics and Its Clinical Applications
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 65
Special Issue Editors
Interests: clinical pharmacokinetics; population PKPD models; pharmacometrics; TDM; model-informed dosing optimization; NONMEM
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Population pharmacokinetics, a field within pharmacokinetics, investigates the variability of drug concentrations between individuals in a selected population. It has gained considerable interest in recent years due to its potential to optimize drug dosing, improve therapeutic outcomes, and minimize adverse effects. This Special Issue focuses on the recent advances in population pharmacokinetics, with an emphasis on the clinical applications for personalized dosing in various therapeutic areas and special populations.
I am pleased to invite you to contribute original research articles, reviews, and methodological papers to this Special Issue entitled Population Pharmacokinetics and Its Clinical Applications. This issue aims to address the increasing demand for personalized medicine and optimized drug therapies. Population pharmacokinetics, a field within pharmacokinetics, investigates the variability in drug concentration among individuals in a selected population. It has gained significant interest in recent years due to its potential to support drug dosing optimization while enhancing therapeutic outcomes and minimizing adverse effects.
This Special Issue focuses on the recent advances in population pharmacokinetics, with an emphasis on the clinical applications for personalized dosing in various therapeutic areas and special populations. The scope of this Special Issue covers a broad range of topics related to population pharmacokinetics, including but not limited to the following: methodological advances in population modeling algorithms and simulation techniques; disease-specific applications of population pharmacokinetics in various therapeutic areas such as infectious diseases, inflammatory bowel diseases, and psychiatric disorders to predict individual patient responses and personalize treatment strategies; pharmacokinetic considerations for special populations such as pediatric, elderly, and patients with comorbidities; the integration of pharmacogenetic data into population pharmacokinetic models; and the potential for genotype-guided dosing strategies. The articles compiled in this Special Issue highlight the evolving landscape of population pharmacokinetics and its role in drug development and clinical practice.
I would like to extend my gratitude to all the authors who have chosen this Special Issue as a platform to publish their research findings. I look forward to receiving your contributions.
Prof. Dr. Katarina Vučićević
Prof. Dr. Branislava Miljković
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- model-informed precision dosing (MIPD)
- therapeutic drug monitoring (TDM)
- dosing adjustments
- special populations
- nonlinear mixed-effects modeling (NONMEM)
- PK/PD models
