Current Research in Drug Metabolism and Drug–Drug Interactions (DDIs)

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 86

Special Issue Editor


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Guest Editor
Department of Pharmaceutical Chemistry, Semmelweis University, 1085 Budapest, Hungary
Interests: in vitro early ADME models; CNS and ophthalmic drug permeability; eye drop formulas; drug metabolism; rheology-mucoadhesivity correlation
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Special Issue Information

Dear Colleagues,

One of the most complex pharmacokinetic characteristics of drug research that covers the entire process is drug metabolism and the associated drug–drug interactions (DDIs). A repeated summary of the new research and development of the field is highly justified and helps the scientific community to identify new problems and outline possible solutions.

In accordance with the above, the Special Issue entitled “Current Research in Drug Metabolism and Drug-Drug Interactions (DDIs)” will consider for publication manuscripts describing the results of original basic and clinical research that contribute significant and novel information on the following topics:

  • The metabolic studies of important existing drugs or known toxicants that address their potential clinical or translational significance;
  • Novel in vivo, in vitro, ex vivo, or in silico model systems for drug metabolism and DDIs, such as 3-D culture, stem cells, and liver-on-a-chip systems;
  • Novel analytical technologies and toolboxes that can be broadly applied to the study of drug metabolism and DDIs;
  • The mechanistic aspects of drug metabolism and DDIs, including the structural studies of formed (reactive) metabolites, enzymes, and transporters and the biochemical studies of nuclear receptors that regulate drug metabolism;
  • The impact of drug metabolism on pharmacokinetics, pharmacodynamics, or drug adverse effects, such as DDIs;
  • The studies of drug metabolism by microbiome or other non-animal species offer new insights into the biological fate of drugs or other xenobiotics in living systems.

I look forward to receiving your contributions.

Prof. Dr. György T. Balogh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pharmacokinetic
  • drug metabolism
  • drug–drug interactions (DDIs)
  • pharmacodynamics
  • drug adverse
  • in vivo
  • in vitro
  • stem cells
  • liver-on-a-chip

Published Papers

This special issue is now open for submission.
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