Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.7
4.6
Journals
Pharmaceuticals
Special Issues
Medication Adherence Issues to Inhaled Therapy and Their Impact on...
share announcement

Medication Adherence Issues to Inhaled Therapy and Their Impact on Lung Diseases

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: closed (15 January 2024) | Viewed by 5363

Special Issue Editors

Dr. Nathalie Wauthoz

E-Mail Website
Guest Editor
Unit of Pharmaceutics and Biopharmaceutics, Department of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université libre de Bruxelles,1050 Brussels, Belgium
Interests: dry powder for inhalation; nanomedicine; cancer; asthma; COPD; lung infections; controlled release; targeting
Prof. Dr. Carine De Vriese

E-Mail Website
Guest Editor
Department of Pharmacotherapy and Pharmaceutics, Faculty of Pharmacy, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium
Interests: medication review; medication adherence; community pharmacy; clinical pharmacy; drug-related problems; implementation science
Prof. Dr. Francesca Buttini

E-Mail Website
Guest Editor
Food and Drug Department, University of Parma, 43124 Parma, Italy
Interests: dry powder inhaler; particle engineering; inhalation therapy; high drug dose
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

“In lung diseases that require chronic treatment such as asthma, COPD or cystic fibrosis,  adherence to inhaled treatments is often poor, leading to poor disease control and exacerbations. Moreover, adherence to the maintenance treatment is more difficult as the patient does not directly feel the benefits on their health status. Moreover, the healthcare professional prescribes the more appropriate medicine for the patient according to the recommendations, but this is sometimes not understandable or not always the easiest for the patient.

Therefore, new strategies to increase adherence are necessary first by identifying the reasons behind a prescription, developing an algorithm to help healthcare professionals in the prescribing procedure, and developing innovative devices and formulations that reduce the adherence problems.

In this Special Issue, the aim is to present articles exploring or reviewing the causes of poor adherence and promising solutions in terms of algorithms, devices, or formulations to overcome them. Patient preferences for a device could include different factors, such as device handling, feedback, and remaining doses/end of product indication, as well as the age of the patient and the disease that they have. Moreover, the device/formulation requires being robust to the patient’s use (inspiratory airflow, inhalation technique, hand–mouth coordination, time of delivery, throughout the product use life) as well as the environmental conditions (temperature and humidity).

This Special Issue aims to cover the main aspects of adherence issues via research articles, reviews, as well as communication, opinions, or brief reports from medical and pharmaceutical experts from academia, industry, and healthcare.”

Dr. Nathalie Wauthoz
Prof. Dr. Carine De Vriese
Prof. Dr. Francesca Buttini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adherence
  • healthcare
  • device
  • dry powder for inhalation
  • pressurized metered device for inhalation
  • dry powder inhaler
  • inhalation technique
  • algorithm
  • device handling
  • feedback

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

17 pages, 667 KiB  
Article
Asthma and COPD: Comparison with International Guidelines and Medication Adherence in Belgium
by Natacha Biset, Mélanie Lelubre, Stéphanie Pochet and Carine De Vriese
Pharmaceuticals 2023, 16(7), 1030; https://doi.org/10.3390/ph16071030 - 20 Jul 2023
Viewed by 1269
Abstract
Asthma and chronic obstructive pulmonary disease (COPD) are major chronic conditions. It is possible to limit their impact by controlling symptoms, which limits exacerbations and worsening of the disease, by choosing the appropriate treatment and ensuring that the patient adheres to it. The [...] Read more.
Asthma and chronic obstructive pulmonary disease (COPD) are major chronic conditions. It is possible to limit their impact by controlling symptoms, which limits exacerbations and worsening of the disease, by choosing the appropriate treatment and ensuring that the patient adheres to it. The main purpose of this study was to assess medication adherence and persistence with inhaled medications for chronic treatment of asthma and COPD, as well as to evaluate the factors influencing this adherence. Medication adherence was measured from January 2013 to December 2016 using continuous multiple-interval measures of medication availability (CMA). Persistence was evaluated by treatment episodes (TE). We analyzed the influence of different factors on CMA such as sex, age, type of device, and the realization of the “new medicines service” (NMS), introduced in Belgium in October 2013 to support patients in adhering to their treatment. We also analyzed the consumption of these inhaled medications within the Belgian population and compared them with the Global Initiative for Asthma (GINA) and the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations. Medication adherence varied greatly between the different pharmacological classes: inhaled corticosteroids (ICS) alone or in combination with long-acting beta agonists (LABA) had the lowest medication adherence and persistence, while adherence was highest for the long-acting muscarinic antagonists (LAMA) and LABA/LAMA associations. The NMS seemed to have a positive impact on medication adherence, although few patients completed the two guidance interviews offered by the service. In addition, only a minority of the targeted patients took advantage of this new service. Full article
(This article belongs to the Special Issue Medication Adherence Issues to Inhaled Therapy and Their Impact on Lung Diseases)
►▼ Show Figures

Figure 1

Other

Jump to: Research

25 pages, 3880 KiB  
Systematic Review
Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis
by Noe Garin, Borja Zarate-Tamames, Laura Gras-Martin, Raimon Milà, Astrid Crespo-Lessmann, Elena Curto, Marta Hernandez, Conxita Mestres and Vicente Plaza
Pharmaceuticals 2023, 16(3), 414; https://doi.org/10.3390/ph16030414 - 8 Mar 2023
Cited by 1 | Viewed by 3590
Abstract
We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus [...] Read more.
We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus and Embase databases, as well as official EMDs websites. We found eight observational studies and ten clinical trials, assessing a wide range of clinical outcomes. Results from the meta-analysis on adherence to inhalers in a period over three months were favourable in the EMD group (fixed effects model: SMD: 0.36 [0.25–0.48]; random effects model SMD: 0.41 [0.22–0.60]). An exploratory meta-analysis found an improvement in ACT score (fixed effect model SMD: 0.25 [0.11–0.39]; random effects model: SMD: 0.47 [−0.14–1.08]). Other clinical outcomes showed mixed results in the descriptive analyses. The findings of this review highlight the benefits of EMDs in the optimization of adherence to inhaled therapy as well as the potential interest in other clinical outcomes. Full article
(This article belongs to the Special Issue Medication Adherence Issues to Inhaled Therapy and Their Impact on Lung Diseases)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop