Raman Spectroscopy: Emerging Technologies and Applications in Biological and Biomedical Fields

A special issue of Optics (ISSN 2673-3269). This special issue belongs to the section "Biomedical Optics".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 4437

Special Issue Editors


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National Research Council - Institute for Photonics and Nanotechnologies (IFN – CNR ) - Department of Physics - Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy
Interests: Raman spectroscopy; Raman imaging; clinical spectroscopy; biophotonics; nanomedicine; biosensors; chemometrics; cancer; calcifications
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Guest Editor
Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy
Interests: biomedical spectroscopy; clinical spectroscopy; Alzheimer’s disease; breast cancer; nanomedicine; raman spectroscopy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Physics and Astronomy, University of Exeter, Stocker Road, Exeter EX4 4QL, UK
Interests: plasmonic nanomaterials; Raman spectroscopy; SERS and SESORS detection; biosensors; cancer diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Raman spectroscopy (RS) has already been proven to be a formidable tool for the study of complex biological processes, detection of specific endogenous biomarkers, assessment of pathological conditions, and disease-site tracking with exogenous contrast agents for diagnostic purposes. RS research has encouraged cross-disciplinary interaction between researchers from different fields,  including physicists, engineers, chemists, biochemists, biologists, biostatisticians, and medical doctors, leading to the development of several Raman-based methods and technologies covering numerous applications in the biomedical field. The field is now also benefitting from the use of the new analytical methods provided by artificial intelligence. These new approaches allow the rapid and accurate analysis of the large volume of data typically generated during the study of biological samples by vibrational spectroscopy.

This Special Issue aims to collect research papers and review articles focused on the evolution of Raman spectroscopy with the aim of answering technological and analytical needs in the biological and medical fields.

To sustain and stimulate the involvement of young and emerging researchers (less than 40 years old at the time of submission), we strongly encourage their participation in a prominent role (first author and/or corresponding author, shared or not with a senior author).

The Special Issue topics include, but are not limited to:

  • Tools and technologies: spontaneous RS, Raman imaging, stimulated RS (e.g., SRS and CARS), nano-enhanced RS (e.g., SERS), deep RS (e.g., SORS and SESORS), RS probes designed or applied to biological/biomedical applications;
  • Applications from biochemical studies to in vivo studies, from cells and tissues to biofluids; and
  • Biostatistical and chemometric tools

You may choose our Joint Special Issue in Applied Sciences.

Dr. Renzo Vanna
Dr. Carlo Morasso
Dr. Priyanka Dey
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Optics is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Raman spectroscopy
  • clinical spectroscopy
  • CRS
  • SERS
  • SORS
  • SESORS
  • artificial intelligence
  • vibrational spectroscopy
  • diagnosis
  • nanotechnology

Published Papers (1 paper)

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Research

7 pages, 634 KiB  
Article
Design Simulation of Czerny–Turner Configuration-Based Raman Spectrometer Using Physical Optics Propagation Algorithm
by Muddasir Naeem, Noor-ul-ain Fatima, Mukhtar Hussain, Tayyab Imran and Arshad Saleem Bhatti
Optics 2022, 3(1), 1-7; https://doi.org/10.3390/opt3010001 - 5 Jan 2022
Cited by 3 | Viewed by 4034
Abstract
We report the design simulation of the Raman spectrometer using Zemax optical system design software. The design is based on the Czerny–Turner configuration, which includes an optical system consisting of an entrance slit, two concave mirrors, reflecting type diffraction grating and an image [...] Read more.
We report the design simulation of the Raman spectrometer using Zemax optical system design software. The design is based on the Czerny–Turner configuration, which includes an optical system consisting of an entrance slit, two concave mirrors, reflecting type diffraction grating and an image detector. The system’s modeling approach is suggested by introducing the corresponding relationship between detector pixels and wavelength, linear CCD receiving surface length and image surface dimension. The simulations were carried out using the POP (physical optics propagation) algorithm. Spot diagram, relative illumination, irradiance plot, modulation transfer function (MTF), geometric and encircled energy were simulated for designing the Raman spectrometer. The simulation results of the Raman spectrometer using a 527 nm wavelength laser as an excitation light source are presented. The present optical system was designed in sequential mode and a Raman spectrum was observed from 530 nm to 630 nm. The analysis shows that the system’s image efficiency was quite good, predicting that it could build an efficient and cost-effective Raman spectrometer for optical diagnostics. Full article
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