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Molecular Photothermal Agents from Design to Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 2818

Special Issue Editor


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Guest Editor
Institute of Chemistry of Rennes, University of Rennes, 35042 Rennes, France
Interests: liquid crystals; metallomesogens; organogelators; metallogelators; supramolecular architecture; ionic self-assembly; stimuli-responsive materials; photothermal activity

Special Issue Information

Dear Colleagues,

During the last decade, photothermal compounds, able to convert light into heat, have found several applications in material sciences, such as actuators or sensors, but also in biotechnologies for imaging and therapy. Many inorganic nanostructures have been studied for their good photothermal properties, such as gold nanorods, carbon nanotubes, 2D transition metal dichalcogenides or superparamagnetic iron oxide nanoparticles, and have found application in various domains. However, inorganic nanostructures often suffer from several drawbacks, such as low stability, toxicity, and low clearance. Organic and organometallic molecules, due to their ease of functionalization, their small molecular size, and their good biocompatibility can be promising alternatives to counterbalance the drawbacks of inorganic nanostructures. Several molecular photothermal agents like cyanines, croconaines, porphyrins, perylenes, and metal-bis(dithiolene) complexes have emerged as efficient photothermal agents and have been used to develop photoresponsive materials and smart theranostic nanosystems. This Special Issue of the journal Molecules is thus devoted to the discovery of new molecular photothermal agents and the application of the photothermal properties of molecules in material science and in biotechnology.

Prof. Franck Camerel
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Photothermal effect
  • Molecular design
  • Organic and coordination chemistry
  • Photophysical properties
  • Light-responsive materials
  • Actuation
  • Soft Robotics
  • Biotechnologies
  • Theranostics
  • Near-infrared light
  • Light conversion

Published Papers (1 paper)

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Research

13 pages, 2511 KiB  
Article
Nanoprecipitation of Biocompatible Poly(malic acid) Derivative, Its Ability to Encapsulate a Molecular Photothermal Agent and Photothermal Properties of the Resulting Nanoparticles
by Marian Gabriela Vargas Guerrero, Jean-Baptiste Pluta, Nathalie Bellec, Sandrine Cammas-Marion and Franck Camerel
Molecules 2021, 26(24), 7703; https://doi.org/10.3390/molecules26247703 - 20 Dec 2021
Cited by 3 | Viewed by 2280
Abstract
Biocompatible nanoparticles (NPs) of hydrophobic poly(benzyl malate) (PMLABe) were prepared by nanoprecipitation. The influence of nanoprecipitation parameters (initial PMLABe, addition rate, organic solvent/water ratio and stirring speed) were studied to optimize the resulting formulations in terms of hydrodynamic diameter (Dh) and dispersity (PDI). [...] Read more.
Biocompatible nanoparticles (NPs) of hydrophobic poly(benzyl malate) (PMLABe) were prepared by nanoprecipitation. The influence of nanoprecipitation parameters (initial PMLABe, addition rate, organic solvent/water ratio and stirring speed) were studied to optimize the resulting formulations in terms of hydrodynamic diameter (Dh) and dispersity (PDI). PMLABe NPs with a Dh of 160 nm and a PDI of 0.11 were isolated using the optimized nanoprecipitation conditions. A hydrophobic near infra-red (NIR) photothermally active nickel-bis(dithiolene) complex (Ni8C12) was then encapsulated into PMLABe NPs using the optimized nanoprecipitation conditions. The size and encapsulation efficiency of the NPs were measured, revealing that up to 50 weight percent (wt%) of Ni8C12 complex can efficiently be encapsulated with a slight increase in Dh of the corresponding Ni8C12-loaded NPs. Moreover, we have shown that NP encapsulating Ni8C12 were stable under storage conditions (4 °C) for at least 10 days. Finally, the photothermal properties of Ni8C12-loaded NPs were evaluated and a high photothermal efficiency (62.7 ± 6.0%) waswas measured with NPs incorporating 10 wt% of the Ni8C12 complex. Full article
(This article belongs to the Special Issue Molecular Photothermal Agents from Design to Applications)
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