Advances in Enantioselective Syntheses and Chiral Separations
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 14288
2. Institute of Chemistry, Jan Dlugosz University in Czestochowa, Armii Krajowej 13/15, 42-200 Czestochowa, Poland
Interests: heterorganic compounds; stereochemistry; synthetic methodology; asymmetric synthesis; supramolecular chemistry; new materials; spectroscopy
Special Issues, Collections and Topics in MDPI journals
For many years, the major factor stimulating the search for optically active compounds was the interest in static and dynamic stereochemistry of organic derivatives with various elements of stereogenity, commonly used as models in mechanistic studies. The search for new enantioselective syntheses and enantioselective separation procedures has been stimulated by the rapid development of medicinal chemistry and biochemistry and, in particular, the needs of the pharmaceutical industry, which is now obliged to study very deeply the biological activity of enantiomeric forms of all chiral drugs before their introduction to the market. This Special Issue will provide a contemporary overview of progress on these two topics. From fundamental aspects to applications, any works related to the generation of new stereogenic units based on chemical and chemoenzymatic methodology are thus welcome. In many cases, when enantioselective synthesis cannot be used to obtain optically active derivatives, chiral separation on a preparative scale remains the method of choice. In addition, analytical chiral separation plays a very important role as a tool that allows very fast and accurate determination of enantiomeric excesses of optically active products isolated by various enantioselective procedures and optically active substances isolated from natural sources. Therefore, all contributions dealing with the analytical aspects of chiral separation are also warmly welcome.
Prof. Józef Drabowicz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- absolute configuration
- asymmetric synthesis
- chiral chromatography
- dynamic kinetic resolution
- elements of stereogenicity enantiomeric excess