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The Latest Trends in Catalyst Immobilization II

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 809

Special Issue Editor


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Guest Editor
Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy
Interests: organic synthesis; stereoselective catalysis; supported catalysts and catalytic reactors; flow chemistry; 3D printing technologies for organic synthesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Considering the success of the first Special Issue in this field, it is my great pleasure to announce the second edition of “The Latest Trends in Catalyst Immobilization”.

Although the anchoring of a catalyst onto a (solid) support is a well-established methodology that dates back into the past, research into this field is still very active. The immobilization of a catalyst offers the possibility of an easy recovery and recycling of the catalyst itself, developments which will facilitate the recovery of the desired product without the need of an extra purification step. For these reasons, immobilized catalysts represent a key tool for the development of a modern and sustainable chemistry. The possibility of confining an immobilized catalyst into a packed-bed reactor, thus realizing a continuous flow process, has paved the way to the development of efficient and sustainable processes that combine the benefits of flow chemistry with the features of immobilized catalysts. Many catalytic reactions with supported catalysts—organic and metal-based, chiral and achiral—have been already implemented in flow, thus making this field more active and attractive. The contribution of biocatalysis to this research area has helped to induce tremendous progress in recent years, placing a powerful methodology in the hands of the synthetic organic chemist for the development of efficient and highly stereoselective catalytic reactions.

This Special Issue, entitled “Latest Trends in Catalyst Immobilization II”, has been prompted by the increasing attention that the field of immobilized catalysts has continuously received. Herein, we will present cutting-edge research works, focusing on both different aspects of catalyst heterogenization (design, synthesis and characterization) and on the use of new catalytic systems in batch and in flow.

Prof. Dr. Alessandra Puglisi
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immobilized catalysts
  • solid support
  • organocatalysis
  • metal catalysis
  • biocatalysis
  • enzymes
  • recyclable catalyst
  • smart materials
  • sustainable process
  • flow chemistry

Published Papers (1 paper)

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Research

14 pages, 1669 KiB  
Article
Various Strategies for the Immobilization of a Phospholipase C from Bacillus cereus for the Modulation of Its Biochemical Properties
by Ines Abdelkader, Jose M. Guisán, Adel Sayari and Gloria Fernández-Lorente
Molecules 2024, 29(7), 1467; https://doi.org/10.3390/molecules29071467 - 26 Mar 2024
Viewed by 471
Abstract
In this study, the effect of various immobilization methods on the biochemical properties of phospholipase C (PLC) from Bacillus cereus obtained from the oily soil located in Sfax, Tunisia, was described. Different supports were checked: octyl sepharose, glyoxyl agarose in the presence of [...] Read more.
In this study, the effect of various immobilization methods on the biochemical properties of phospholipase C (PLC) from Bacillus cereus obtained from the oily soil located in Sfax, Tunisia, was described. Different supports were checked: octyl sepharose, glyoxyl agarose in the presence of N-acetyl cysteine, and Q-sepharose. In the immobilization by hydrophobic adsorption, a hyperactivation of the PLCBc was obtained with a fold of around 2 times. The recovery activity after immobilization on Q-sepharose and glyoxyl agarose in the presence of N-acetyl cysteine was 80% and 58%, respectively. Furthermore, the biochemical characterization showed an important improvement in the three immobilized enzymes. The performance of the various immobilized PLCBc was compared with the soluble enzyme. The derivatives acquired using Q-sepharose, octyl sepharose, and glyoxyl agarose were stable at 50 °C, 60 °C, and 70 °C. Nevertheless, the three derivatives were more stable in a large range of pH than the soluble enzyme. The three derivatives and the free enzyme were stable in 50% (v/v) ethanol, hexane, methanol, and acetone. The glyoxyl agarose derivative showed high long-term storage at 4 °C, with an activity of 60% after 19 days. These results suggest the sustainable biotechnological application of the developed immobilized enzyme. Full article
(This article belongs to the Special Issue The Latest Trends in Catalyst Immobilization II)
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