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Polymer Biosensor for Electrochemical Detection

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Macromolecular Chemistry".

Deadline for manuscript submissions: closed (30 April 2020) | Viewed by 10014

Special Issue Editor


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Guest Editor
Departament d’Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/Eduard Maristany, 10-14, Ed. I2, 08019 Barcelona, Spain
Interests: conducting polymers; biodegradable polymers; electrochemical sensors; controlled drug delivery systems; electro-stimulation; solid-state supercapacitors; molecular dynamics simulations

Special Issue Information

Dear Colleagues,

Electrochemical biosensors have been attracting much attention thanks to the major advantages in their use, such as short analysis times, when compared with spectroscopic techniques. Moreover, they may be used in simple experimental procedures which can be applied to a variety of physiological samples. Within this context, conducting polymers are being extensively studied as coatings of bare electrodes to significantly enhance the sensitivity and selectivity of bioanalytical detection. Thus, conducting polymers are versatile materials for the creation of electrochemical biosensors, due to their rapid production, controlled thickness, and porosity, as well as easy electropolymerization on various surfaces. Moreover, the recent introduction of new non-invasive electrochemical sensors fills the niche left by invasive sensors, which can cause reluctance among patients, and advanced sensor technologies which are desired for mobile health monitoring and remote diagnosis.

This Special Issue of Molecules aims to present useful insights into the latest advances and current trends in the field of polymeric electrochemical biosensors. Original research and review articles that discuss the preparation of electrochemical sensors based on conducting polymers, for their applications in health, diagnosis, biomedicine, and so forth, are welcome.

Prof. Carlos Alemán
Guest Editor

Manuscript Submission Information

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Keywords

  • electrochemical biosensors
  • conducting polymers
  • healthcare
  • biomarker detection
  • biomedical diagnosis
  • selective and sensitive monitoring

Published Papers (2 papers)

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Review

37 pages, 7742 KiB  
Review
Polymers and Plastics Modified Electrodes for Biosensors: A Review
by Sonia Lanzalaco and Brenda G. Molina
Molecules 2020, 25(10), 2446; https://doi.org/10.3390/molecules25102446 - 24 May 2020
Cited by 20 | Viewed by 4606
Abstract
Polymer materials offer several advantages as supports of biosensing platforms in terms of flexibility, weight, conformability, portability, cost, disposability and scope for integration. The present study reviews the field of electrochemical biosensors fabricated on modified plastics and polymers, focusing the attention, in the [...] Read more.
Polymer materials offer several advantages as supports of biosensing platforms in terms of flexibility, weight, conformability, portability, cost, disposability and scope for integration. The present study reviews the field of electrochemical biosensors fabricated on modified plastics and polymers, focusing the attention, in the first part, on modified conducting polymers to improve sensitivity, selectivity, biocompatibility and mechanical properties, whereas the second part is dedicated to modified “environmentally friendly” polymers to improve the electrical properties. These ecofriendly polymers are divided into three main classes: bioplastics made from natural sources, biodegradable plastics made from traditional petrochemicals and eco/recycled plastics, which are made from recycled plastic materials rather than from raw petrochemicals. Finally, flexible and wearable lab-on-a-chip (LOC) biosensing devices, based on plastic supports, are also discussed. This review is timely due to the significant advances achieved over the last few years in the area of electrochemical biosensors based on modified polymers and aims to direct the readers to emerging trends in this field. Full article
(This article belongs to the Special Issue Polymer Biosensor for Electrochemical Detection)
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11 pages, 1850 KiB  
Review
Application of Conducting Polymer Nanostructures to Electrochemical Biosensors
by Waleed A. El-Said, Muhammad Abdelshakour, Jin-Ha Choi and Jeong-Woo Choi
Molecules 2020, 25(2), 307; https://doi.org/10.3390/molecules25020307 - 12 Jan 2020
Cited by 68 | Viewed by 4958
Abstract
Over the past few decades, nanostructured conducting polymers have received great attention in several application fields, including biosensors, microelectronics, polymer batteries, actuators, energy conversion, and biological applications due to their excellent conductivity, stability, and ease of preparation. In the bioengineering application field, the [...] Read more.
Over the past few decades, nanostructured conducting polymers have received great attention in several application fields, including biosensors, microelectronics, polymer batteries, actuators, energy conversion, and biological applications due to their excellent conductivity, stability, and ease of preparation. In the bioengineering application field, the conducting polymers were reported as excellent matrixes for the functionalization of various biological molecules and thus enhanced their performances as biosensors. In addition, combinations of metals or metal oxides nanostructures with conducting polymers result in enhancing the stability and sensitivity as the biosensing platform. Therefore, several methods have been reported for developing homogeneous metal/metal oxide nanostructures thin layer on the conducting polymer surfaces. This review will introduce the fabrications of different conducting polymers nanostructures and their composites with different shapes. We will exhibit the different techniques that can be used to develop conducting polymers nanostructures and to investigate their chemical, physical and topographical effects. Among the various biosensors, we will focus on conducting polymer-integrated electrochemical biosensors for monitoring important biological targets such as DNA, proteins, peptides, and other biological biomarkers, in addition to their applications as cell-based chips. Furthermore, the fabrication and applications of the molecularly imprinted polymer-based biosensors will be addressed in this review. Full article
(This article belongs to the Special Issue Polymer Biosensor for Electrochemical Detection)
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