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Hyaluronan II

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 1471

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Guest Editor
Centre of Experimental Medicine of Slovak Academy of Sciences, Dubravska cesta 9, 84104 Bratislava, Slovakia
Interests: hyaluronan; reactive oxygen species; drugs; antioxidants; biopolymers
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Special Issue Information

Dear Colleagues,

Hyaluronan (HA) is a natural glycosaminoglycan present in many tissues in all vertebrates. HA has various biological functions, which depend on its molar mass. HA has antioxidant properties; however, it can be readily degraded by reactive oxygen species. For many years, it has been used in the treatment of osteoarthritis, in ophthalmology, and in cosmetics. In recent years, there has been a growing interest in applying HA in other fields of medicine such as dentistry, skin wound healing, gene delivery, and tissue engineering.

Dr. Katarína Valachová
Guest Editor

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Keywords

  • hyaluronan
  • hyaluronan degradation
  • cosmetics
  • medicine
  • reactive oxygen species

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Published Papers (1 paper)

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Review

15 pages, 1461 KiB  
Review
Hyaluronan: Sources, Structure, Features and Applications
by Katarína Valachová, Mohamed E. Hassan and Ladislav Šoltés
Molecules 2024, 29(3), 739; https://doi.org/10.3390/molecules29030739 - 05 Feb 2024
Viewed by 1249
Abstract
Hyaluronan (HA) is a non-sulfated glycosaminoglycan that is present in a variety of body tissues and organs. Hyaluronan has a wide range of biological activities that are frequently influenced by molar mass; however, they also depend greatly on the source, purity, and kind [...] Read more.
Hyaluronan (HA) is a non-sulfated glycosaminoglycan that is present in a variety of body tissues and organs. Hyaluronan has a wide range of biological activities that are frequently influenced by molar mass; however, they also depend greatly on the source, purity, and kind of impurities in hyaluronan. High-molar-mass HA has anti-inflammatory, immunosuppressive, and antiangiogenic properties, while low-molar-mass HA has opposite properties. A number of chemical modifications have been performed to enhance the stability of HA and its applications in medical practice. Hyaluronan is widely applied in medicine, such as viscosupplementation, ophthalmology, otolaryngology, wound healing, cosmetics, and drug delivery. In this review, we summarized several medical applications of polymers based on the hyaluronan backbone. Full article
(This article belongs to the Special Issue Hyaluronan II)
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