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Bioactive Compounds from Functional Foods, 2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Food Chemistry".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 1095

Special Issue Editors


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Guest Editor
Department of Food Product Quality, Cracow University of Economics, Sienkiewicza 5, 30-033 Kraków, Poland
Interests: traditional, regional and organic foods; bioactive compounds in foods; enriched bakery products; food product development; food quality; food authentication
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Guest Editor
Department of Food Chemistry and Analysis, Institute of Food Technology and Food Chemistry, Technische Universität Berlin, Gustav-Meyer-Allee 25, D-13355 Berlin, Germany
Interests: food proteins; secondary plant metabolites; compound stability and interactions
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Functional foods are still gaining widespread consumer interest, mainly due to their beneficial effects on humans. Their actions are primarily connected with the content of bioactive compounds. These compounds are mainly plant secondary metabolites (e.g., flavonoids, carotenoids, and phenolic acids) utilized in recipes as pan extracts or sometimes as pure compounds. However, primary plant metabolites and sometimes compounds from animal sources (e.g., selected peptides, vitamins, minerals, and fatty acids), as well as compounds from other sources such as single cells (e.g., yeasts, bacteria, and algae) can be considered functional ingredients. Biologically active compounds demonstrate various positive physiological and immunological functions. Some act as antioxidant agents and thus can diminish the risk of various diseases, including cancer. Others stimulate defense mechanisms, prevent widespread damage, or enhance cell repair. One of the limitations of the application of functional ingredients is their stability, but other main challenges include finding optimal concentrations and recipes.

This Special Issue of Molecules aims to bring together the latest knowledge, ideas, considerations, and overviews on bioactive compounds that can be found in functional foods. We will highly appreciate contributions related to the identification and roles of bioactive functional food constituents, as well as all aspects of the challenges mentioned above. Original research and review articles on the enhancement of foods with functional, biologically active ingredients are also welcome.

Dr. Michał Halagarda
Prof. Dr. Sascha Rohn
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functional foods
  • biological activities
  • secondary metabolites
  • phytonutrients
  • nutraceuticals
  • new foods and formulations
  • bioactive potential
  • functional characterization
  • isolation of bioactives

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Published Papers (1 paper)

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Research

13 pages, 894 KiB  
Article
Quantification of Trimethylamine-N-Oxide and Trimethylamine in Fish Oils for Human Consumption
by Dominik Dörfel, Sascha Rohn and Eckard Jantzen
Molecules 2024, 29(6), 1339; https://doi.org/10.3390/molecules29061339 - 17 Mar 2024
Viewed by 855
Abstract
Supplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine-N-oxide, a recently emerged risk factor for cardiovascular disease, as well as [...] Read more.
Supplementing fish oil is one of the strategies to reduce the risk of cardiovascular disease, the leading cause of death around the world. Contradictorily, fish oil may also contain trimethylamine-N-oxide, a recently emerged risk factor for cardiovascular disease, as well as one of its precursors, trimethylamine. A method suitable for routine quantification of trimethylamine-N-oxide and trimethylamine in fish oil with a quick and easy liquid extraction without derivatization has been developed. Liquid chromatography with tandem mass spectrometry detection was employed along with a zwitterionic hydrophilic interaction liquid chromatography column and a gradient elution with eluents containing 50 mmol/L of ammonium formate. An internal standard (triethylamine) was used for quantification by mass spectrometry with an external calibration. The assay proved high linearity in the ranges of 10 to 100 ng/mL and 100 to 1000 ng/mL for trimethylamine-N-oxide and trimethylamine, respectively. The lowest limit of quantification was determined to be 100 µg/kg for trimethylamine and 10 µg/kg for trimethylamine-N-oxide, with the limit of detection at 5 µg/kg and 0.25 µg/kg, respectively. Accuracy ranged from 106–119%. Precision was below 7% the relative standard deviation for both analytes. The method was successfully applied for the determination of trimethylamine-N-oxide and trimethylamine contents in nine commercially available liquid fish oils and three commercially available fish oil capsules, showing that trimethylamine and trimethylamine-N-oxide are not present in highly refined fish oils. Full article
(This article belongs to the Special Issue Bioactive Compounds from Functional Foods, 2nd Edition)
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