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Preparation, Characterization, and Application of Degradable and Antibacterial Materials

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1915

Special Issue Editor


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Guest Editor
Pacific Northwest National Laboratory (PNNL), Richland, WA 99354, USA
Interests: biodegradable polymers and composites; self-healing and shape memory polymers; plant oil-based polyurethane; biocompatible polymers for biomedical applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Approximately 367 million metric tons of global petroleum-based polymers were produced in 2020 and their consumption is forecast to double by 2050. Petroleum-based plastics are not sustainable and might exacerbate the risk for air, water, and soil pollutions. Bio-based and biodegradable polymers with outstanding mechanical, thermal, chemical, and biological properties have been recently developed as alternatives to petroleum-based counterparts. There are many cost-effective sustainable environmentally friendly feedstocks or biomass that can be utilized to produce bio-based polymers and composites. Wood, lignocellulose, starch, sugars, proteins, and plant oils are the most widely used renewable feedstocks in making different bio-based polymers for different applications. Biodegradable polymers have been developed to fulfill most of the functions of petroleum-based materials in applications ranging from packaging to durable goods and have a major advantage over nonbiodegradable polymers in terms of degradation. The aim of this Special Issue is to cover new research topics related to biodegradable and antibacterial polymers, blends, gels, dispersions, and composites, from renewable resources, bacterial fermentation, and polymerization of biomonomers. Studies on the characterization, processing, rheology, shape-memory effect, self-healing, applications, and life cycle assessment of different types of bio-based and/or biodegradable polymers and composites are within the scope of this Special Issue. Researchers are cordially invited to contribute original research and review articles to this Special Issue.

Dr. Samy Madbouly
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biodegradable polymers
  • antibacterial polymers
  • bio-based polymers
  • bio-renewable polymers
  • bio-based fibers and fillers
  • biodegradation mechanism
  • processing and characterization
  • life cycle assessment
  • applications of biodegradable polymers

Published Papers (2 papers)

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Research

9 pages, 3686 KiB  
Communication
A Modified Tridecapeptide Probe for Imaging Cell Junction
by Jingrui Li, Yuhan Wu, Chunyu Liu, Shu Zhang, Xin Su, Songbo Xie and Fengtang Yang
Molecules 2024, 29(5), 1003; https://doi.org/10.3390/molecules29051003 - 25 Feb 2024
Viewed by 619
Abstract
Cell junctions, which are typically associated with dynamic cytoskeletons, are essential for a wide range of cellular activities, including cell migration, cell communication, barrier function and signal transduction. Observing cell junctions in real-time can help us understand the mechanisms by which they regulate [...] Read more.
Cell junctions, which are typically associated with dynamic cytoskeletons, are essential for a wide range of cellular activities, including cell migration, cell communication, barrier function and signal transduction. Observing cell junctions in real-time can help us understand the mechanisms by which they regulate these cellular activities. This study examined the binding capacity of a modified tridecapeptide from Connexin 43 (Cx43) to the cell junction protein zonula occludens-1 (ZO-1). The goal was to create a fluorescent peptide that can label cell junctions. A cell-penetrating peptide was linked to the modified tridecapeptide. The heterotrimeric peptide molecule was then synthesized. The binding of the modified tridecapeptide was tested using pulldown and immunoprecipitation assays. The ability of the peptide to label cell junctions was assessed by adding it to fixed or live Caco-2 cells. The testing assays revealed that the Cx43-derived peptide can bind to ZO-1. Additionally, the peptide was able to label cell junctions of fixed cells, although no obvious cell junction labeling was observed clearly in live cells, probably due to the inadequate affinity. These findings suggest that labeling cell junctions using a peptide-based strategy is feasible. Further efforts to improve its affinity are warranted in the future. Full article
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13 pages, 1063 KiB  
Article
Development of a Strategy for L-Lactic Acid Production by Rhizopus oryzae Using Zizania latifolia Waste and Cane Molasses as Carbon Sources
by Feng-Wei Yin, Xiao-Long Sun, Wei-Long Zheng, Long-Fei Yin, Xi Luo, Ying-Ying Zhang, Yan-Fei Wang and Yong-Qian Fu
Molecules 2023, 28(17), 6234; https://doi.org/10.3390/molecules28176234 - 24 Aug 2023
Cited by 2 | Viewed by 1063
Abstract
As a biodegradable and renewable material, polylactic acid is considered a major environmentally friendly alternative to petrochemical plastics. Microbial fermentation is the traditional method for lactic acid production, but it is still too expensive to compete with the petrochemical industry. Agro-industrial wastes are [...] Read more.
As a biodegradable and renewable material, polylactic acid is considered a major environmentally friendly alternative to petrochemical plastics. Microbial fermentation is the traditional method for lactic acid production, but it is still too expensive to compete with the petrochemical industry. Agro-industrial wastes are generated from the food and agricultural industries and agricultural practices. The utilization of agro-industrial wastes is an important way to reduce costs, save energy and achieve sustainable development. The present study aimed to develop a method for the valorization of Zizania latifolia waste and cane molasses as carbon sources for L-lactic acid fermentation using Rhizopus oryzae LA-UN-1. The results showed that xylose derived from the acid hydrolysis of Z. latifolia waste was beneficial for cell growth, while glucose from the acid hydrolysis of Z. latifolia waste and mixed sugars (glucose and fructose) from the acid hydrolysis of cane molasses were suitable for the accumulation of lactic acid. Thus, a three-stage carbon source utilization strategy was developed, which markedly improved lactic acid production and productivity, respectively reaching 129.47 g/L and 1.51 g/L·h after 86 h of fermentation. This work demonstrates that inexpensive Z. latifolia waste and cane molasses can be suitable carbon sources for lactic acid production, offering an efficient utilization strategy for agro-industrial wastes. Full article
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