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Research of Organic Chemicals for Biological Applications-Volume Ⅱ

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 October 2024 | Viewed by 75

Special Issue Editors


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Guest Editor
Life Science Department, University of Modena and Reggio Emilia, Modena, Italy
Interests: medicinal chemistry; synthesis of sigma and 5-HT1A receptor ligands; DAT and HDAC6 inhibitors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Drug Sciences, University of Pavia, Pavia, Italy
Interests: medicinal chemistry; antimicrobial resistance; b-lactamases; quorum sensing; synthesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Drugs are chemicals used for medicinal purposes. They interact with complex human chemical systems. For this reason, organic chemicals and biology are closely related and the role of chemistry in the discovery and manufacture of new drugs is crucial.

This Special Issue covers research in medicinal chemistry, organic synthesis and analytical chemistry, areas useful for the rational design, synthesis and characterization of small molecules endowed with biological activity, particularly those of pharmaceutical relevance.

We welcome contributions on the most interesting developments in the areas of organic chemistry, medicinal chemistry and chemical biology.

These should focus on the rational design and structural optimization of hits and leads (i.e., computational, chemical, biophysical sciences), and the application of these technologies to modern pharmaceutical research.

The support of organic chemistry in the identification of new molecular targets through the synthesis of small-molecule modulators of characterized (structure-based drug design, SBDD), or non-characterized biological targets (ligand-based drug design, LBDD).

The development of advanced synthetic methodologies (such as organo-catalyzed, stereo-controlled, solvent-free, high-pressure and microwave-assisted synthetic procedures) and chemical technologies (such as flow chemistry, electrochemistry, and photocatalysis), which directly affect the synthesis of new drug-like molecules or simply of new chemical entities. Particular attention will be paid to the development and application of environmentally sustainable synthetic techniques in view of the current global green transition.

The application of advanced spectroscopic and spectrometric techniques (NMR, LC-(HR)MS, UV, and FT-IR) useful to structurally characterize the synthesized new organic molecules, to study the ligand-receptor interactions, and to develop new biologically active molecules that have been discovered. Full papers, communications, and reviews are welcome in this Special Issue.

Dr. Claudia Sorbi
Dr. Pasquale Linciano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicinal chemistry
  • organic chemistry
  • organic synthesis
  • biological targets
  • therapeutics
  • drug design
  • drug analysis
  • pharmaceutical analysis

Related Special Issue

Published Papers

This special issue is now open for submission.
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