molecules-logo

Journal Browser

Journal Browser

Organic Transformations Promoted by 3d Metal Complexes: Synthetic Applications and Mechanisms

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organometallic Chemistry".

Deadline for manuscript submissions: closed (15 December 2019) | Viewed by 6070

Special Issue Editor


E-Mail Website
Guest Editor
Department of Chemistry, Southern Methodist University, Dallas, TX, USA

Special Issue Information

Dear Colleagues,

Metalloenzymes use bioavailable nontoxic metals (Fe, Cu, Mn, Zn, etc.) and green oxidants, such as O2 or H2O2, to promote the biosynthesis of organic molecules under very mild conditions with exquisite product selectivity. On the other hand, most of the organic synthetic protocols found in industrial processes rely on the utilization of expensive 4d and 5d metals such as Pd or Pt, which usually also require harsh reaction conditions.

In this special issue, we will compile some of the most significant and recent research contributions that report the use of 3d metal complexes to promote the functionalization of organic molecules, including work inspired by the reactivity of metalloenzymes.

Dr. Isaac Garcia-Bosch
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • C-H functionalizations
  • Oxidations
  • Reductions
  • Bioinspired catalysis
  • Coupling reactions
  • 3d metals
  • Benign oxidants

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

22 pages, 3971 KiB  
Article
Biomimetic Non-Heme Iron-Catalyzed Epoxidation of Challenging Terminal Alkenes Using Aqueous H2O2 as an Environmentally Friendly Oxidant
by Anja Fingerhut, Jorge Vargas-Caporali, Marco Antonio Leyva-Ramírez, Eusebio Juaristi and Svetlana B. Tsogoeva
Molecules 2019, 24(17), 3182; https://doi.org/10.3390/molecules24173182 - 01 Sep 2019
Cited by 1 | Viewed by 5777
Abstract
Catalysis mediated by iron complexes is emerging as an eco-friendly and inexpensive option in comparison to traditional metal catalysis. The epoxidation of alkenes constitutes an attractive application of iron(III) catalysis, in which terminal olefins are challenging substrates. Herein, we describe our study on [...] Read more.
Catalysis mediated by iron complexes is emerging as an eco-friendly and inexpensive option in comparison to traditional metal catalysis. The epoxidation of alkenes constitutes an attractive application of iron(III) catalysis, in which terminal olefins are challenging substrates. Herein, we describe our study on the design of biomimetic non-heme ligands for the in situ generation of iron(III) complexes and their evaluation as potential catalysts in epoxidation of terminal olefins. Since it is well-known that active sites of oxidases might involve imidazole fragment of histidine, various simple imidazole derivatives (seven compounds) were initially evaluated in order to find the best reaction conditions and to develop, subsequently, more elaborated amino acid-derived peptide-like chiral ligands (10 derivatives) for enantioselective epoxidations. Full article
Show Figures

Graphical abstract

Back to TopTop