Immune System on a Chip: State-of-the-Art Micro-Engineered Models
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 394
Special Issue Editors
Interests: organs-on-chips; micro- and nanofabrication; microfluidics; immune system
Special Issues, Collections and Topics in MDPI journals
Interests: micro and nano fabrication; microfluidics; organs-on-chip; image analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Our immune system orchestrates a host defense in a complex relationship of molecules, cells, and organs organizing smart weapons factories and communication stations.
In the age of immunotherapy and single-cell genomic profiling, immunologists need to take advantage of emerging in vitro tools to capture heterogeneity in the immune response and function in complex disease models in a proper spatiotemporal context.
Nowadays, state-of-the-art microengineered cellular models such as organoids, microphysiological systems (MPSs), and organs-on-chips (OOCs) have begun to simulate immunological aspects in a variety of processes ranging from inflammatory states to infectious diseases and tumor-on-chip microenvironments.
The coupling of these models with high-content microscopy and advanced image processing approaches may enhance the ability to see the immunological context and extract quantitative data at the single-cell level from engineered cellular ecosystems.
This Special Issue will highlight novel microsystems and coculture methods (e.g, organoids, OOCs, MPSs) for visualizing and monitoring immune system activities and dynamics.
Dr. Adele De NinnoDr. Luca Businaro
Guest Editors
Manuscript Submission Information
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Keywords
- immune response on a chip
- infection
- inflammation
- immune organs and cells
