Recent Advances in Lab-on-a-Chip and Their Biomedical Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 813

Special Issue Editors


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Guest Editor
Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China
Interests: microfluidics/manofluidics; lab on a chip; nanotoxicology; numercial simulations

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Guest Editor
Institute for Health Innovation & Technology (iHealthtech), National University of Singapore, Singapore 117599, Singapore
Interests: organ on a chip; drug screening; cell mechanobiology

Special Issue Information

Dear Colleague,

This Special Issue, "Recent Advances in Lab-on-a-Chip and Their Biomedical Applications", serves as a platform to showcase the latest breakthroughs and innovations in the field of lab-on-a-chip (LOC) technology and its diverse applications in biomedicine. Lab-on-a-chip platforms have revolutionized medical diagnostics, drug discovery, and biomedical research by providing miniaturized, integrated systems that offer high precision and efficiency.

This Special Issue seeks to gather research papers and review articles focusing on the current state of LOC technology, from the development of microfluidic devices to their biomedical applications. It welcomes contributions from researchers and experts across various disciplines who are exploring the integration of LOC systems into medical diagnostics, point-of-care testing, and drug development. It also encompasses a wide range of topics, including microfabrication techniques, bioanalytical methods, biomarker detection, single-cell analysis, and the miniaturization of laboratory processes, and highlights the translation of LOC technologies into clinical practice and their role in improving patient care and outcomes.

By fostering collaboration and knowledge exchange among scientists, engineers, and healthcare professionals, this Special Issue aims to accelerate the adoption of lab-on-a-chip platforms in biomedicine. We invite submissions that reflect the latest advancements and innovative applications contributing to the ongoing transformation of healthcare and the advancement of biomedical research.

We look forward to receiving your submissions.

Prof. Dr. Guoqing Hu
Dr. Xiaoyan Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lab on a chip
  • organ on a chip
  • microfluidics
  • biomedical applications
  • drug screening
  • high-throughput analysis
  • point-of-care diagnostics
  • lab-on-a-chip devices
  • microfluidic separation
  • disease diagnosis
  • biochips
  • micrototal analysis systems (μTASs)

Published Papers (1 paper)

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Research

12 pages, 10693 KiB  
Article
Capillary Force-Driven Quantitative Plasma Separation Method for Application of Whole Blood Detection Microfluidic Chip
by Xiaohua Fang, Cuimin Sun, Peng Dai, Zhaokun Xian, Wenyun Su, Chaowen Zheng, Dong Xing, Xiaotian Xu and Hui You
Micromachines 2024, 15(5), 619; https://doi.org/10.3390/mi15050619 - 1 May 2024
Viewed by 607
Abstract
Separating plasma or serum from blood is essential for precise testing. However, extracting precise plasma quantities outside the laboratory poses challenges. A recent study has introduced a capillary force-driven membrane filtration technique to accurately separate small plasma volumes. This method efficiently isolates 100–200 [...] Read more.
Separating plasma or serum from blood is essential for precise testing. However, extracting precise plasma quantities outside the laboratory poses challenges. A recent study has introduced a capillary force-driven membrane filtration technique to accurately separate small plasma volumes. This method efficiently isolates 100–200 μL of pure human whole blood with a 48% hematocrit, resulting in 5–30 μL of plasma with less than a 10% margin of error. The entire process is completed within 20 min, offering a simple and cost-effective approach to blood separation. This study has successfully addressed the bottleneck in self-service POCT, ensuring testing accuracy. This innovative method shows promise for clinical diagnostics and point-of-care testing. Full article
(This article belongs to the Special Issue Recent Advances in Lab-on-a-Chip and Their Biomedical Applications)
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