Mechanisms of Airway Inflammation in Asthma
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".
Deadline for manuscript submissions: 20 July 2024 | Viewed by 93
Special Issue Editor
Special Issue Information
Dear Colleagues,
Recently, our understanding of inflammation in asthma has changed dramatically. This change has been driven in part by studies examining inflammation in patients with severe asthma, who have the greatest burden of asthma morbidity and mortality. These investigations have provided a deeper understanding of key factors modulating inflammation in asthma and have identified multiple phenotypes within asthma. While eosinophilic and Type 2 inflammation are critical inflammatory pathways for many asthmatics, other asthma patients have predominantly non-Type 2 inflammation, such as patients with obesity-associated asthma and patients with neutrophilic-predominant asthma. A greater understanding of the inflammatory processes in asthma has led to novel therapies targeting specific molecular targets. Additionally, the detailed characterization of inflammatory mechanisms active in different asthma phenotypes has facilitated the targeting of therapies to those patients most likely to respond. This individualized treatment approach allows patients to achieve greater control of their disease while minimizing the use of medications with long-term severe side effects, such as systemic steroids. This special issue of Journal of Personalized Medicine will review several of the major advances in our knowledge regarding inflammation in asthma and how this heightened understanding of the pathophysiology of asthma has led to innovative therapeutic approaches for this disease.
Dr. Kathleen Haley
Guest Editor
Manuscript Submission Information
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Keywords
- asthma
- inflammation in asthma
- targeted therapies
- acute respiratory distress syndrome
- chronic lung diseases
- critical care
