Mechanisms of Airway Inflammation in Asthma

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 20 July 2024 | Viewed by 120

Special Issue Editor


E-Mail Website
Guest Editor
Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA
Interests: pulmonary hypertension; asthma; acute respiratory distress syndrome; critical care

Special Issue Information

Dear Colleagues,

Recently, our understanding of inflammation in asthma has changed dramatically. This change has been driven in part by studies examining inflammation in patients with severe asthma, who have the greatest burden of asthma morbidity and mortality. These investigations have provided a deeper understanding of key factors modulating inflammation in asthma and have identified multiple phenotypes within asthma. While eosinophilic and Type 2 inflammation are critical inflammatory pathways for many asthmatics, other asthma patients have predominantly non-Type 2 inflammation, such as patients with obesity-associated asthma and patients with neutrophilic-predominant asthma. A greater understanding of the inflammatory processes in asthma has led to novel therapies targeting specific molecular targets. Additionally, the detailed characterization of inflammatory mechanisms active in different asthma phenotypes has facilitated the targeting of therapies to those patients most likely to respond. This individualized treatment approach allows patients to achieve greater control of their disease while minimizing the use of medications with long-term severe side effects, such as systemic steroids. This special issue of Journal of Personalized Medicine will review several of the major advances in our knowledge regarding inflammation in asthma and how this heightened understanding of the pathophysiology of asthma has led to innovative therapeutic approaches for this disease.

Dr. Kathleen Haley
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • asthma
  • inflammation in asthma
  • targeted therapies
  • acute respiratory distress syndrome
  • chronic lung diseases
  • critical care

Published Papers

This special issue is now open for submission.
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