Phenotypic Screening in Drug Discovery
A special issue of High-Throughput (ISSN 2571-5135).
Deadline for manuscript submissions: closed (31 December 2018) | Viewed by 215
Special Issue Editor
Special Issue Information
This Special Issue invites contributions from the field of complex in vitro disease models and phenotypic screening—including high content screening approaches. The focus should be on cell- and tissue-based, physiologically-relevant model systems for a broad spectrum of diseases. Ideally, some of the aspects that make up functional tissues should be addressed and included, such as the extracellular matrix and the interaction of various cell types that recapitulate various characteristics of normal or diseased tissue architectures. The contributions can include three-dimensional cell culture and co-culture methods, microfluidics, and tools for the quantitative assessment of phenotypic characteristics, such as automated image analyses and/or machine learning tools for computational image analyses.
We aim towards including a relatively broad spectrum of technical, but also biological novelties in the field, which will contribute to the future development of phenotypic (drug) screens in applied and academic research.
Prof. Matthias Nees
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. High-Throughput is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- high content screening
- high throughput screening
- physiologically relevant model sytems
