Psycho-Bio-Social Factors to Drive Frailty: What’s New?

A special issue of Geriatrics (ISSN 2308-3417). This special issue belongs to the section "Geriatric Psychiatry and Psychology".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 607

Special Issue Editors

E-Mail Website
Guest Editor
Polytechnic Institute of Coimbra, Applied Research Institute, Rua da Misericórdia, Lagar dos Cortiços–S. Martinho do Bispo, 3045-093 Coimbra, Portugal
Interests: psychobiological of exercise; frailty and sarcopenia; changes in behavior; active life style promotion; health literacy
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Post-Graduate Program in Health Science, Santo Amaro University (UNISA), Santo Amaro 04743-030, SP, Brazil
Interests: exercise Immunology; mucosal Immunology; immunosenescence; inflammaging

E-Mail Website
Guest Editor
Interdisciplinary Program in Health Sciences, Institute of Physical Activity Sciences and Sports (ICAFE), Cruzeiro do Sul University, São Paulo, SP, Brazil
Interests: oxidative stress; antioxidants; exercise; free radicals; redox biology

Special Issue Information

Dear Colleagues,

There is a long history in scientific research targeting frail people and their condition. Indeed, several methods have been applied to accurately assess frailty, including the Frailty Index and the Physical Frailty, which, altogether, contributed significantly to our understanding of this worrying condition. The grouping of several frailty indexes or measures to create a composite score for frailty was a huge improvement in establishing a robust criterium for frailty identification and classification. For example, consider the cognitive frailty (concomitant physical and cognitive declines), which, based on the similarity of the two clinical outcomes, develops a specific method for assessing this phenotypic subgroup. Regardless of several varieties of screen methods, the presence of frailty is associated with a variety of negative outcomes and poor stress tolerance and is a risk factor for the increase of unfavorable health outcomes.

On the other hand, recent evidence indicates that older adults who engage in more physical activity (systematic or not) are less likely to develop frailty and its associated clinical outcomes. Furthermore, there is strong evidence that exercise can reduce and reverse the frailty condition, taking multifactorial interventions into account. From the frailty of biological systems (i.e., immune, neuroendocrine), we move on to the recent emphasis on oral frailty, also highlighting that isolation and loneliness can characterize social frailty.

In this regard, we invite all colleagues to submit studies demonstrating the existence of new ‘Psycho-bio-social’ correlated of frailty. Epidemiological, systematic reviews of any types and interventional studies approaching physical exercise or multifactorial interventions (in combination with exercise) will be appreciated. Research protocol articles will be accepted as long as they present novel study designs for understanding frailty in older populations.

Dr. Guilherme Furtado
Dr. André Luis Lacerda Bachi
Prof. Dr. Marcelo Barros
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Geriatrics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • frailty
  • active lifestyle
  • older adults
  • health status
  • multifactorial interventions

Published Papers

This special issue is now open for submission.
Back to TopTop